C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphodiesterase 4A, cAMP specific
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032177 Pde4a 10090 + 9:21165714-21213248 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003395 Pde4a-003 21196705-21211627 protein_coding
  ENSMUST00000039413 Pde4a-001 21165714-21213248 protein_coding
  ENSMUST00000115458 Pde4a-002 21184103-21211627 protein_coding
  ENSMUST00000127821 Pde4a-006 21192197-21194759 retained_intron
  ENSMUST00000131769 Pde4a-004 21181616-21211627 retained_intron
  ENSMUST00000140440 Pde4a-005 21184101-21193498 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003395ENSMUST00000039413ENSMUST00000115458ENSMUST00000131769
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003395 N/A N/A N/A 7.542±5.24 N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.826±0.00
ENSMUST00000039413 0.785±0.22 1.368±0.74 1.852±0.06 3.355±0.68 1.285±0.41 0.513±0.13 1.958±0.00 0.702±0.27 0.272±0.13 1.762±0.55 N/A 0.963±0.37 0.925±0.43 N/A
ENSMUST00000115458 1.347±0.28 3.052±0.49 N/A 7.910±0.00 1.949±0.58 0.780±0.24 4.759±0.00 N/A 0.415±0.18 1.043±0.05 2.538±0.00 1.093±0.34 0.571±0.00 N/A
ENSMUST00000131769 1.253±0.29 1.386±0.24 0.568±0.00 N/A 0.839±0.00 0.662±0.12 N/A 0.462±0.08 0.217±0.06 N/A N/A 1.070±0.34 0.551±0.20 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00037J CIL_00037J_0002 CGP 9:21138541-21213248
CIL_0004FB CIL_0004FB_0002 CGP 9:21165714-21239332

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004114 IDA 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 ISS 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0006198 IEA cAMP catabolic process
GO:0007165 IEA signal transduction
GO:0007608 IGI sensory perception of smell
GO:0010738 IMP regulation of protein kinase A signaling
GO:0030552 IEA cAMP binding
GO:0035690 IDA cellular response to drug
GO:0043949 IMP regulation of cAMP-mediated signaling
GO:0046872 IEA metal ion binding
GO:0048471 IEA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032344 pde4a phosphodiesterase 4A, cAMP-specific protein_coding Danio_rerio
ENSG00000065989 PDE4A phosphodiesterase 4A, cAMP-specific protein_coding Homo_sapiens

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