C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tropomyosin 1, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032366 Tpm1 10090 - 9:67022590-67049406 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030185 Tpm1-002 67028848-67049262 protein_coding
  ENSMUST00000034928 Tpm1-008 67022593-67049209 protein_coding
  ENSMUST00000050905 Tpm1-004 67027892-67049264 protein_coding
  ENSMUST00000113684 Tpm1-020 67028048-67043733 protein_coding
  ENSMUST00000113685 Tpm1-003 67027892-67049213 protein_coding
  ENSMUST00000113686 Tpm1-014 67027966-67043841 protein_coding
  ENSMUST00000113687 Tpm1-012 67027989-67049143 protein_coding
  ENSMUST00000113689 Tpm1-021 67024326-67043709 protein_coding
  ENSMUST00000113690 Tpm1-013 67022593-67043962 protein_coding
  ENSMUST00000113693 Tpm1-011 67024324-67049172 protein_coding
  ENSMUST00000113695 Tpm1-016 67022592-67043802 protein_coding
  ENSMUST00000113696 Tpm1-015 67022590-67043907 protein_coding
  ENSMUST00000113697 Tpm1-006 67022615-67049275 protein_coding
  ENSMUST00000113701 Tpm1-010 67022606-67049201 protein_coding
  ENSMUST00000113705 Tpm1-007 67022590-67049267 protein_coding
  ENSMUST00000113707 Tpm1-001 67022590-67049406 protein_coding
  ENSMUST00000129466 Tpm1-019 67032220-67049118 retained_intron
  ENSMUST00000129733 Tpm1-009 67022606-67049186 nonsense_mediated_decay
  ENSMUST00000131279 Tpm1-018 67033778-67049191 processed_transcript
  ENSMUST00000139046 Tpm1-017 67022622-67043778 nonsense_mediated_decay
  ENSMUST00000156899 Tpm1-005 67029920-67032825 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000050905ENSMUST00000113684ENSMUST00000113685ENSMUST00000113686ENSMUST00000113687ENSMUST00000113690ENSMUST00000113693ENSMUST00000113695ENSMUST00000113696ENSMUST00000113697ENSMUST00000113701ENSMUST00000113705ENSMUST00000129733ENSMUST00000131279
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000050905 N/A N/A N/A N/A N/A N/A N/A 22.996±4.93 N/A N/A N/A N/A N/A N/A
ENSMUST00000113684 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.764±0.00
ENSMUST00000113685 N/A N/A N/A N/A 647.476±220.69 N/A 4074.935±342.25 27.054±4.83 N/A 145.722±8.93 13369.800±356.72 N/A N/A N/A
ENSMUST00000113686 N/A 49.855±17.45 N/A 69.064±0.00 18.389±0.00 96.716±20.41 N/A N/A 4.363±1.14 96.577±0.00 N/A 73.729±10.85 N/A N/A
ENSMUST00000113687 N/A N/A N/A 56.522±0.00 N/A N/A N/A N/A N/A N/A N/A 622.033±0.00 454.604±109.82 6.513±0.00
ENSMUST00000113690 N/A 5.773±1.43 N/A 17.850±4.62 7.284±0.00 28.406±2.68 N/A N/A 10.258±0.00 N/A N/A 22.644±0.36 N/A N/A
ENSMUST00000113693 N/A N/A N/A 47.172±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000113695 N/A 12.460±0.00 N/A 19.948±0.00 N/A N/A N/A 18.965±5.78 10.148±10.04 64.793±19.51 N/A 157.573±13.51 103.589±21.86 2.813±0.00
ENSMUST00000113696 19.803±1.60 18.454±6.13 N/A 14.165±1.89 25.569±4.52 N/A N/A 18.647±1.77 34.365±32.96 48.968±10.13 N/A 45.011±2.61 N/A 2.703±0.00
ENSMUST00000113697 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 73.982±2.77 179.618±90.87 N/A
ENSMUST00000113701 N/A N/A N/A N/A N/A 197.112±22.86 N/A 10.203±0.00 N/A N/A N/A 80.257±33.48 95.230±0.00 2.882±1.15
ENSMUST00000113705 92.397±76.47 N/A 2725.800±235.79 N/A 8.984±0.00 108.173±19.07 N/A 13.367±2.12 N/A 34.699±0.00 N/A 60.968±12.79 91.908±42.35 8.449±4.37
ENSMUST00000129733 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 214.334±100.71 N/A
ENSMUST00000131279 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 490.002±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00098V CIL_00098V_0002 VISTA 9:66700483-67304558
CIL_00094O CIL_00094O_0002 VISTA 9:66740666-67343521
CIL_0004OW CIL_0004OW_0002 CGP 9:66955393-67049406
CIL_0005H2 CIL_0005H2_0002 CGP 9:67022590-67559703

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001725 IEA stress fiber
GO:0003065 IMP positive regulation of heart rate by epinephrine
GO:0003779 IEA actin binding
GO:0005200 TAS structural constituent of cytoskeleton
GO:0005737 IDA cytoplasm
GO:0005862 TAS muscle thin filament tropomyosin
GO:0008092 IEA cytoskeletal protein binding
GO:0030016 IDA myofibril
GO:0031941 IDA filamentous actin
GO:0032059 IEA bleb
GO:0032587 IEA ruffle membrane
GO:0034614 IEA cellular response to reactive oxygen species
GO:0045214 IEA sarcomere organization
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087402 TPM1 protein_coding Danio_rerio
ENSG00000140416 TPM1 tropomyosin 1 (alpha) protein_coding Homo_sapiens

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