C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myeloid differentiation primary response gene 88
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032508 Myd88 10090 - 9:119335934-119341411 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035092 Myd88-001 119335934-119340041 protein_coding
  ENSMUST00000139870 Myd88-003 119339690-119341411 protein_coding
  ENSMUST00000150837 Myd88-002 119335946-119340002 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastHeartLiverLungMuscleOvaryPlacentaTestisENSMUST00000035092
Transcript ID Adipose Bladder Breast Heart Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035092 15.047±1.00 10.044±0.00 14.010±1.87 5.312±0.37 6.496±0.66 16.078±1.29 2.670±0.68 15.447±5.78 18.908±8.39 4.591±2.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BE CIL_0008BE_0002 VISTA 9:119196374-119798584
CIL_000131 CIL_000131_0002 CGP 9:119238432-119341411

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002238 IMP response to molecule of fungal origin
GO:0002755 IGI MyD88-dependent toll-like receptor signaling pathway
GO:0005102 IEA receptor binding
GO:0005121 IEA Toll binding
GO:0005149 IEA interleukin-1 receptor binding
GO:0005515 IPI protein binding
GO:0005737 TAS cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006954 IEA inflammatory response
GO:0006955 TAS immune response
GO:0007166 IMP cell surface receptor signaling pathway
GO:0007178 TAS transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0007254 IEA JNK cascade
GO:0008063 IEA Toll signaling pathway
GO:0009615 IMP response to virus
GO:0014069 IEA postsynaptic density
GO:0016064 IMP immunoglobulin mediated immune response
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0031663 IMP lipopolysaccharide-mediated signaling pathway
GO:0032494 IMP response to peptidoglycan
GO:0032496 IMP response to lipopolysaccharide
GO:0032740 IMP positive regulation of interleukin-17 production
GO:0032747 IMP positive regulation of interleukin-23 production
GO:0032755 IMP positive regulation of interleukin-6 production
GO:0032760 IMP positive regulation of tumor necrosis factor production
GO:0042127 IGI regulation of cell proliferation
GO:0043123 IGI positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043234 IEA protein complex
GO:0044130 IMP negative regulation of growth of symbiont in host
GO:0045080 IGI positive regulation of chemokine biosynthetic process
GO:0045087 IEA innate immune response
GO:0045351 IMP type I interferon biosynthetic process
GO:0046330 IMP positive regulation of JNK cascade
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0050671 IMP positive regulation of lymphocyte proliferation
GO:0050727 IMP regulation of inflammatory response
GO:0050830 IMP defense response to Gram-positive bacterium
GO:0051092 IGI positive regulation of NF-kappaB transcription factor activity
GO:0070976 IEA TIR domain binding
GO:0090557 IMP establishment of endothelial intestinal barrier

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010169 myd88 myeloid differentiation primary response gene (88) protein_coding Danio_rerio
ENSG00000172936 MYD88 myeloid differentiation primary response 88 protein_coding Homo_sapiens

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