C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mesencephalic astrocyte-derived neurotrophic factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032575 Manf 10090 - 9:106838312-106891979 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069036 Manf-002 106888762-106891415 protein_coding
  ENSMUST00000159283 Manf-001 106887415-106891979 protein_coding
  ENSMUST00000159620 Manf-007 106838312-106891872 protein_coding
  ENSMUST00000160503 Manf-005 106889084-106891870 protein_coding
  ENSMUST00000160978 Manf-004 106890031-106891915 protein_coding
  ENSMUST00000161272 Manf-006 106869198-106890283 protein_coding
  ENSMUST00000162801 Manf-003 106890562-106891917 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000069036ENSMUST00000159283ENSMUST00000160978ENSMUST00000162801
Transcript ID Adrenal Bladder Brain Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000069036 N/A 28.109±4.38 41.110±0.00 N/A N/A 36.453±6.71 N/A 5.651±0.89 111.950±69.24 215.813±170.44 96.397±0.00
ENSMUST00000159283 N/A N/A N/A 9.367±0.00 6.490±0.00 7.795±2.61 10.055±2.66 N/A 21.912±0.00 25.723±1.40 35.516±8.50
ENSMUST00000160978 172.090±18.55 N/A N/A N/A 47.402±0.00 64.500±20.96 N/A N/A N/A 121.128±16.47 N/A
ENSMUST00000162801 135.029±32.82 N/A N/A 60.118±0.00 N/A 53.860±8.79 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005MV CIL_0005MV_0003 CGP 9:106838312-106891979

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002014 IDA vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure
GO:0003674 ND molecular_function
GO:0005575 ND cellular_component
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005783 IEA endoplasmic reticulum
GO:0044822 IEA poly(A) RNA binding
GO:0048471 IEA perinuclear region of cytoplasm

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063177 manf mesencephalic astrocyte-derived neurotrophic factor protein_coding Danio_rerio
ENSG00000145050 MANF mesencephalic astrocyte-derived neurotrophic factor protein_coding Homo_sapiens

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