C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MyoD family inhibitor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032717 Mdfi 10090 - 17:47815328-47834691 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035375 Mdfi-003 47815336-47833291 protein_coding
  ENSMUST00000066368 Mdfi-001 47815328-47834691 protein_coding
  ENSMUST00000113280 Mdfi-008 47815328-47833241 protein_coding
  ENSMUST00000125745 Mdfi-007 47815921-47833258 processed_transcript
  ENSMUST00000129360 Mdfi-005 47824599-47833230 protein_coding
  ENSMUST00000131971 Mdfi-009 47816039-47833169 protein_coding
  ENSMUST00000132125 Mdfi-004 47820926-47833245 protein_coding
  ENSMUST00000140234 Mdfi-002 47819798-47833261 retained_intron
  ENSMUST00000152455 Mdfi-006 47820837-47833272 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035375ENSMUST00000066368ENSMUST00000113280ENSMUST00000125745ENSMUST00000132125ENSMUST00000140234ENSMUST00000152455
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035375 2.881±1.38 1.816±0.56 3.453±0.22 3.528±0.41 6.551±2.43 2.199±0.37 1.977±0.41 1.161±0.32 1.524±1.23 6.473±1.23 0.248±0.07 27.695±10.61 21.746±12.72 0.345±0.00
ENSMUST00000066368 0.986±0.00 0.733±0.23 N/A N/A 2.460±0.77 0.880±0.05 N/A 0.224±0.04 0.065±0.01 1.603±0.21 N/A 5.886±0.80 5.635±0.00 0.129±0.06
ENSMUST00000113280 N/A N/A N/A 0.607±0.00 N/A N/A N/A N/A N/A N/A 0.268±0.05 15.041±0.00 17.556±3.17 N/A
ENSMUST00000125745 N/A N/A N/A N/A N/A N/A 0.896±0.00 N/A N/A N/A 0.108±0.00 N/A 12.549±5.56 0.165±0.06
ENSMUST00000132125 N/A N/A N/A 0.914±0.00 N/A N/A N/A N/A N/A N/A N/A 62.499±0.00 69.113±6.37 N/A
ENSMUST00000140234 N/A N/A N/A N/A N/A N/A N/A N/A 0.089±0.00 N/A 0.061±0.00 1.189±0.00 N/A N/A
ENSMUST00000152455 N/A N/A N/A N/A 6.531±0.00 N/A 1.159±0.01 0.540±0.12 N/A N/A 0.227±0.10 27.619±0.00 N/A 0.203±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000963 CIL_000963_0002 VISTA 17:47571879-48173076
CIL_00093V CIL_00093V_0002 VISTA 17:47614773-48215356
CIL_0008XI CIL_0008XI_0002 VISTA 17:47688296-48291797
CIL_0008IB CIL_0008IB_0002 VISTA 17:47708185-48309224
CIL_0007QG CIL_0007QG_0002 VISTA 17:47710565-48311720
CIL_0008F3 CIL_0008F3_0002 VISTA 17:47757242-48358147

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007257 IDA activation of JUN kinase activity
GO:0008134 IPI transcription factor binding
GO:0009950 IMP dorsal/ventral axis specification
GO:0030111 IDA regulation of Wnt signaling pathway
GO:0030178 IGI negative regulation of Wnt signaling pathway
GO:0043392 IDA negative regulation of DNA binding
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0060707 IMP trophoblast giant cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000089564 MDFI MyoD family inhibitor protein_coding Danio_rerio
ENSG00000112559 MDFI MyoD family inhibitor protein_coding Homo_sapiens

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