C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033016 Nfatc1 10090 - 18:80606205-80713071 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035800 Nfatc1-201 80647435-80708173 protein_coding
  ENSMUST00000078049 Nfatc1-202 80606205-80713071 protein_coding
  ENSMUST00000167977 Nfatc1-203 80606205-80708173 protein_coding
  ENSMUST00000170905 Nfatc1-204 80606205-80713071 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035800ENSMUST00000078049ENSMUST00000167977ENSMUST00000170905
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035800 2.627±0.25 3.641±0.51 0.646±0.36 0.212±0.14 8.095±3.67 3.319±0.93 1.626±0.47 1.461±0.15 1.248±0.49 5.316±1.45 2.349±0.25 1.782±0.65 0.783±0.95 0.154±0.01
ENSMUST00000078049 0.992±0.16 0.591±0.07 0.463±0.00 0.161±0.06 2.790±0.94 0.998±0.13 0.755±0.00 N/A 0.264±0.01 N/A 3.160±1.34 0.621±0.18 0.554±0.35 N/A
ENSMUST00000167977 1.101±0.28 1.607±0.31 0.232±0.00 0.363±0.17 2.508±0.74 1.410±0.37 0.931±0.46 0.663±0.15 0.417±0.18 2.237±0.07 3.037±0.84 0.584±0.14 0.750±0.54 0.065±0.00
ENSMUST00000170905 0.602±0.00 N/A N/A 0.102±0.00 2.345±0.57 1.044±0.00 0.377±0.00 N/A N/A 2.501±0.00 1.142±0.07 0.283±0.00 0.235±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007Y9 CIL_0007Y9_0002 VISTA 18:80030119-80632361
CIL_0008HP CIL_0008HP_0002 VISTA 18:80487642-81088565
CIL_0008IX CIL_0008IX_0002 VISTA 18:80511437-81112175
CIL_0008KF CIL_0008KF_0002 VISTA 18:80518312-81119092

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000790 IEA nuclear chromatin
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001837 IMP epithelial to mesenchymal transition
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006816 IMP calcium ion transport
GO:0007507 IMP heart development
GO:0010628 IDA positive regulation of gene expression
GO:0030316 IGI osteoclast differentiation
GO:0035556 ISO intracellular signal transduction
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045893 ISO positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036168 nfatc1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 protein_coding Danio_rerio
ENSG00000131196 NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 protein_coding Homo_sapiens

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