C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 4A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033326 Kdm4a 10090 - 4:118136957-118180043 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050288 Kdm4a-003 118142043-118179946 protein_coding
  ENSMUST00000097911 Kdm4a-002 118136959-118179654 protein_coding
  ENSMUST00000106403 Kdm4a-005 118137006-118179978 protein_coding
  ENSMUST00000106406 Kdm4a-001 118136957-118180043 protein_coding
  ENSMUST00000152808 Kdm4a-004 118145785-118146759 processed_transcript
  ENSMUST00000164821 Kdm4a-006 118149051-118161657 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000097911ENSMUST00000106403ENSMUST00000106406
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000097911 3.188±0.00 11.698±7.73 N/A N/A 5.337±1.22 3.319±0.49 N/A N/A 1.895±0.05 5.654±1.46 3.048±1.30 11.628±3.06 12.453±0.00 N/A
ENSMUST00000106403 6.036±2.78 6.175±1.49 N/A 7.023±0.00 4.682±1.64 8.277±4.34 N/A 3.975±0.46 2.121±0.31 5.374±2.07 1.157±0.16 12.355±4.35 3.625±0.34 1.948±0.48
ENSMUST00000106406 7.068±2.67 3.539±0.00 8.396±1.05 13.894±7.37 4.704±0.62 5.213±1.66 5.404±1.06 6.475±1.01 3.356±1.31 5.388±1.83 3.266±1.02 6.258±2.84 8.150±3.51 3.447±1.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002F2 CIL_0002F2_0002 CGP 4:117932154-118180043

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0014898 IMP cardiac muscle hypertrophy in response to stress
GO:0016577 IEA histone demethylation
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035064 ISS methylated histone binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0051864 IEA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IEA histone H3-K36 demethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018782 KDM4A (1 of 2) lysine (K)-specific demethylase 4A protein_coding Danio_rerio
ENSDARG00000019103 kdm4ab lysine (K)-specific demethylase 4A, genome duplicate b protein_coding Danio_rerio
ENSG00000066135 KDM4A lysine (K)-specific demethylase 4A protein_coding Homo_sapiens

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