C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 4A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000106406 Kdm4a-001 ENSMUSG00000033326 10090 - 4:118136957-118180043 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000106406
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000106406 7.068±2.67 3.539±0.00 8.396±1.05 13.894±7.37 4.704±0.62 5.213±1.66 5.404±1.06 6.475±1.01 3.356±1.31 5.388±1.83 3.266±1.02 6.258±2.84 8.150±3.51 3.447±1.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002F2 CIL_0002F2_0002 CGP 4:117932154-118180043

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0014898 IMP cardiac muscle hypertrophy in response to stress
GO:0016577 IEA histone demethylation
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035064 ISS methylated histone binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0051864 IEA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IEA histone H3-K36 demethylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000372396 KDM4A-001 protein_coding Homo_sapiens 0 3818
ENST00000463151 KDM4A-002 processed_transcript Homo_sapiens 0 1066
ENST00000472265 KDM4A-005 processed_transcript Homo_sapiens 0 309
ENST00000485249 KDM4A-003 processed_transcript Homo_sapiens 0 885
ENST00000616726 RP11-60C6.8-001 unprocessed_pseudogene Homo_sapiens 0.00000000003 73

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