C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 4A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000066135 KDM4A 9606 + 1:43650158-43705515 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372396 KDM4A-001 43650158-43705515 protein_coding
  ENST00000463151 KDM4A-002 43650536-43667021 processed_transcript
  ENST00000472265 KDM4A-005 43666285-43667062 processed_transcript
  ENST00000481296 KDM4A-004 43690590-43692278 processed_transcript
  ENST00000485249 KDM4A-003 43653306-43667021 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372396ENST00000485249
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372396 4.764±0.00 3.761±0.00 N/A 3.513±2.08 3.838±2.41 2.269±0.38 2.184±1.61 4.718±1.95 1.267±0.36 2.756±0.15 2.541±1.16 4.923±3.91 6.946±1.33 2.066±0.90
ENST00000485249 N/A N/A 2.568±0.00 N/A N/A N/A N/A N/A N/A N/A 2.016±0.00 4.298±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005B7 CIL_0005B7_0002 CGP 1:43525187-43705515
CIL_0005B8 CIL_0005B8_0002 CGP 1:43650158-43931165

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0014898 IEA cardiac muscle hypertrophy in response to stress
GO:0016032 IEA viral process
GO:0016577 IDA histone demethylation
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035064 IDA methylated histone binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0051864 IDA histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 IDA histone H3-K36 demethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018782 KDM4A (1 of 2) lysine (K)-specific demethylase 4A protein_coding Danio_rerio
ENSDARG00000019103 kdm4ab lysine (K)-specific demethylase 4A, genome duplicate b protein_coding Danio_rerio
ENSMUSG00000033326 Kdm4a lysine (K)-specific demethylase 4A protein_coding Mus_musculus

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