C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033542 Arhgef5 10090 + 6:43265582-43289320 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031750 Arhgef5-001 43265582-43289320 protein_coding
  ENSMUST00000182190 Arhgef5-005 43279457-43289316 retained_intron
  ENSMUST00000182647 Arhgef5-008 43282882-43284015 retained_intron
  ENSMUST00000182752 Arhgef5-007 43280990-43283566 retained_intron
  ENSMUST00000182924 Arhgef5-002 43274511-43289319 protein_coding
  ENSMUST00000183094 Arhgef5-004 43277047-43287195 retained_intron
  ENSMUST00000183227 Arhgef5-003 43276938-43279920 retained_intron
  ENSMUST00000183313 Arhgef5-006 43282614-43289315 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031750ENSMUST00000182190ENSMUST00000182924
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031750 4.818±1.90 3.906±1.05 8.293±0.16 0.776±0.11 2.814±0.76 14.604±3.50 3.308±0.73 10.514±1.74 2.432±1.18 12.100±0.42 1.272±0.32 6.613±2.69 27.297±14.21 0.457±0.11
ENSMUST00000182190 1.805±0.84 N/A 6.459±0.63 0.331±0.00 N/A N/A N/A N/A 0.996±0.57 N/A 0.330±0.02 4.853±0.00 5.241±0.00 0.240±0.07
ENSMUST00000182924 N/A N/A N/A 0.274±0.00 N/A N/A 1.025±0.00 3.845±0.40 1.093±0.32 N/A 0.501±0.01 2.960±0.00 N/A 0.169±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074V CIL_00074V_0002 CGP 6:43235578-43289320
CIL_00074U CIL_00074U_0002 CGP 6:43265582-43309554

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002408 IMP myeloid dendritic cell chemotaxis
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0030036 IDA actin cytoskeleton organization
GO:0032319 IEA regulation of Rho GTPase activity
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0071803 IGI positive regulation of podosome assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076383 ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 protein_coding Danio_rerio
ENSG00000050327 ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5 protein_coding Homo_sapiens

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