C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000031750 Arhgef5-001 ENSMUSG00000033542 10090 + 6:43265582-43289320 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031750
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031750 4.818±1.90 3.906±1.05 8.293±0.16 0.776±0.11 2.814±0.76 14.604±3.50 3.308±0.73 10.514±1.74 2.432±1.18 12.100±0.42 1.272±0.32 6.613±2.69 27.297±14.21 0.457±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00074V CIL_00074V_0002 CGP 6:43235578-43289320
CIL_00074U CIL_00074U_0002 CGP 6:43265582-43309554

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002408 IMP myeloid dendritic cell chemotaxis
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0030036 IDA actin cytoskeleton organization
GO:0032319 IEA regulation of Rho GTPase activity
GO:0032321 IDA positive regulation of Rho GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0071803 IGI positive regulation of podosome assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000056217 ARHGEF5-001 protein_coding Homo_sapiens 0 2651
ENST00000378115 ARHGEF35-001 protein_coding Homo_sapiens 0 255
ENST00000471847 ARHGEF5-005 protein_coding Homo_sapiens 0 1943
ENST00000474817 ARHGEF5-002 protein_coding Homo_sapiens 0 1801
ENST00000483587 ARHGEF34P-001 unprocessed_pseudogene Homo_sapiens 0 2228
ENST00000498580 ARHGEF5-004 protein_coding Homo_sapiens 0 268

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