C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin VI
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000033577 Myo6 10090 + 9:80165031-80311729 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035889 Myo6-001 80165031-80311729 protein_coding
  ENSMUST00000076140 Myo6-003 80217637-80311729 protein_coding
  ENSMUST00000113266 Myo6-004 80217629-80311729 protein_coding
  ENSMUST00000113268 Myo6-002 80165040-80311728 protein_coding
  ENSMUST00000127779 Myo6-014 80217611-80308050 protein_coding
  ENSMUST00000130496 Myo6-005 80262047-80266671 retained_intron
  ENSMUST00000138650 Myo6-009 80306914-80308602 retained_intron
  ENSMUST00000139981 Myo6-007 80286281-80292611 retained_intron
  ENSMUST00000143804 Myo6-008 80305771-80307795 processed_transcript
  ENSMUST00000156199 Myo6-006 80285414-80286508 retained_intron
  ENSMUST00000183377 Myo6-011 80165038-80168028 retained_intron
  ENSMUST00000184480 Myo6-012 80165227-80308097 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035889ENSMUST00000076140ENSMUST00000113266ENSMUST00000127779ENSMUST00000138650ENSMUST00000139981ENSMUST00000184480
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035889 N/A 2.902±0.00 N/A 5.761±0.00 N/A 5.547±0.68 N/A N/A N/A 4.829±2.10 0.592±0.18 5.530±2.49 0.841±0.00 0.903±0.12
ENSMUST00000076140 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.300±0.00 2.132±0.00 N/A
ENSMUST00000113266 N/A N/A N/A N/A N/A 7.385±0.00 0.549±0.00 N/A 1.124±0.00 N/A 0.450±0.04 12.954±3.04 3.099±2.10 0.889±0.52
ENSMUST00000127779 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.551±0.16 N/A N/A N/A
ENSMUST00000138650 4.712±1.54 8.698±0.47 3.762±0.00 N/A 3.771±0.45 20.109±4.25 N/A 23.958±2.45 3.202±1.80 9.534±0.34 1.829±0.12 14.018±1.41 14.172±8.67 N/A
ENSMUST00000139981 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.044±0.00
ENSMUST00000184480 N/A N/A N/A 8.641±0.00 N/A 8.520±0.00 N/A N/A N/A N/A N/A 10.577±0.00 2.151±0.01 0.622±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PS CIL_0006PS_0002 CGP 9:80066903-80311729
CIL_0006PV CIL_0006PV_0002 CGP 9:80165031-80465481

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001726 IEA ruffle
GO:0003774 IEA motor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005654 IEA nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IPI plasma membrane
GO:0005902 IEA microvillus
GO:0006605 IPI protein targeting
GO:0006897 IMP endocytosis
GO:0007268 IMP synaptic transmission
GO:0007416 IMP synapse assembly
GO:0007605 IMP sensory perception of sound
GO:0007626 IMP locomotory behavior
GO:0008152 IEA metabolic process
GO:0012506 IPI vesicle membrane
GO:0014047 IMP glutamate secretion
GO:0016020 IEA membrane
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0016358 IMP dendrite development
GO:0016459 IEA myosin complex
GO:0016591 IEA DNA-directed RNA polymerase II, holoenzyme
GO:0030139 IEA endocytic vesicle
GO:0030330 IEA DNA damage response, signal transduction by p53 class mediator
GO:0030424 IDA axon
GO:0031941 IEA filamentous actin
GO:0031965 IEA nuclear membrane
GO:0032587 IEA ruffle membrane
GO:0042472 IMP inner ear morphogenesis
GO:0042491 IMP auditory receptor cell differentiation
GO:0042493 IEA response to drug
GO:0043025 IDA neuronal cell body
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IEA protein complex
GO:0045177 IEA apical part of cell
GO:0045202 ISO synapse
GO:0045334 IEA clathrin-coated endocytic vesicle
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048167 IMP regulation of synaptic plasticity
GO:0048471 ISO perinuclear region of cytoplasm
GO:0048839 IMP inner ear development
GO:0051015 ISO actin filament binding
GO:0051046 IEA regulation of secretion
GO:0070062 IEA extracellular vesicular exosome
GO:0071257 IMP cellular response to electrical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042141 myo6b myosin VIb protein_coding Danio_rerio
ENSG00000196586 MYO6 myosin VI protein_coding Homo_sapiens

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