C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: son of sevenless homolog 2 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034801 Sos2 10090 - 12:69583762-69681852 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035773 Sos2-001 69583766-69681852 protein_coding
  ENSMUST00000182123 Sos2-002 69583762-69587119 retained_intron
  ENSMUST00000182396 Sos2-006 69585089-69681627 protein_coding
  ENSMUST00000182646 Sos2-004 69585375-69588806 retained_intron
  ENSMUST00000182838 Sos2-005 69594406-69596822 retained_intron
  ENSMUST00000183277 Sos2-007 69584853-69681841 protein_coding
  ENSMUST00000183306 Sos2-003 69614446-69617119 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035773ENSMUST00000182123ENSMUST00000182396ENSMUST00000182838ENSMUST00000183277
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035773 1.678±0.60 N/A 1.307±0.00 1.668±0.00 1.523±0.49 N/A 1.309±0.27 1.720±0.00 0.715±0.09 1.289±0.00 1.817±0.42 2.630±1.80 1.117±0.36 0.875±0.00
ENSMUST00000182123 2.215±0.00 N/A N/A N/A 3.496±0.00 N/A 1.943±0.07 3.068±0.50 N/A 4.838±1.20 N/A 4.235±1.06 N/A 0.915±0.10
ENSMUST00000182396 N/A N/A N/A N/A N/A N/A N/A N/A 0.714±0.06 N/A 1.542±0.10 3.425±0.00 2.935±0.59 0.426±0.00
ENSMUST00000182838 N/A N/A N/A N/A N/A N/A N/A N/A 1.725±0.39 N/A N/A 3.212±0.00 N/A N/A
ENSMUST00000183277 3.754±0.72 2.899±0.76 5.140±0.50 5.304±0.87 5.285±2.50 2.774±1.08 4.707±0.39 5.859±1.14 2.244±0.71 7.118±0.35 3.316±1.01 4.703±1.79 3.192±0.62 1.791±0.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016A CIL_00016A_0002 CGP 12:69577628-69681852
CIL_0005HL CIL_0005HL_0003 CGP 12:69583762-69724874

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005088 IMP Ras guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0007264 IMP small GTPase mediated signal transduction
GO:0032320 IMP positive regulation of Ras GTPase activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043547 IDA positive regulation of GTPase activity
GO:0046982 IEA protein heterodimerization activity
GO:0051057 IEA positive regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060506 sos2 son of sevenless homolog 2 (Drosophila) protein_coding Danio_rerio
ENSG00000100485 SOS2 son of sevenless homolog 2 (Drosophila) protein_coding Homo_sapiens

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