C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: son of sevenless homolog 2 (Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000182396 Sos2-006 ENSMUSG00000034801 10090 - 12:69585089-69681627 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverMuscleOvaryPlacentaTestisENSMUST00000182396
Transcript ID Liver Muscle Ovary Placenta Testis
ENSMUST00000182396 0.714±0.06 1.542±0.10 3.425±0.00 2.935±0.59 0.426±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016A CIL_00016A_0002 CGP 12:69577628-69681852
CIL_0005HL CIL_0005HL_0003 CGP 12:69583762-69724874

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005085 IDA guanyl-nucleotide exchange factor activity
GO:0005088 IMP Ras guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005622 IEA intracellular
GO:0007264 IMP small GTPase mediated signal transduction
GO:0032320 IMP positive regulation of Ras GTPase activity
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043547 IDA positive regulation of GTPase activity
GO:0046982 IEA protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000216373 SOS2-001 protein_coding Homo_sapiens 0 3482
ENST00000543680 SOS2-002 protein_coding Homo_sapiens 0 4824
ENST00000555666 SOS2-005 processed_transcript Homo_sapiens 0 599
ENST00000555794 SOS2-003 protein_coding Homo_sapiens 0 1096
ENST00000556452 SOS2-004 nonsense_mediated_decay Homo_sapiens 0 244
ENST00000556469 SOS2-006 processed_transcript Homo_sapiens 0 691

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