C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: helicase, POLQ-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035266 Helq 10090 - 5:100762145-100798598 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044684 Helq-001 100762145-100798598 protein_coding
  ENSMUST00000133845 Helq-003 100762447-100798468 protein_coding
  ENSMUST00000135102 Helq-007 100771548-100774120 retained_intron
  ENSMUST00000138417 Helq-009 100762456-100766813 retained_intron
  ENSMUST00000139203 Helq-010 100762151-100765438 retained_intron
  ENSMUST00000144948 Helq-005 100791772-100793052 retained_intron
  ENSMUST00000151201 Helq-002 100783180-100798577 nonsense_mediated_decay
  ENSMUST00000152554 Helq-006 100778385-100783000 retained_intron
  ENSMUST00000155362 Helq-008 100766737-100774036 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044684ENSMUST00000133845ENSMUST00000135102ENSMUST00000138417ENSMUST00000139203ENSMUST00000151201ENSMUST00000155362
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044684 0.952±0.08 0.456±0.06 1.527±0.06 2.554±1.06 0.665±0.17 0.856±0.11 0.381±0.11 0.915±0.23 2.270±1.94 0.596±0.14 0.430±0.11 1.018±0.34 2.384±1.12 0.973±0.45
ENSMUST00000133845 N/A N/A N/A 0.433±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000135102 N/A N/A N/A 4.120±0.00 N/A N/A N/A N/A N/A N/A N/A 5.381±0.00 5.126±3.38 1.689±0.00
ENSMUST00000138417 N/A N/A N/A 4.958±0.00 N/A N/A N/A 2.952±0.45 1.150±0.00 N/A N/A N/A N/A 2.830±0.00
ENSMUST00000139203 N/A N/A 1.504±0.00 N/A N/A N/A 0.417±0.00 1.090±0.00 0.676±0.46 N/A 0.610±0.00 N/A N/A N/A
ENSMUST00000151201 N/A 1.064±0.40 N/A 1.303±0.00 1.265±0.02 1.477±0.49 N/A 0.658±0.00 0.352±0.18 N/A N/A 2.133±0.31 2.712±1.73 N/A
ENSMUST00000155362 N/A 1.172±0.14 N/A N/A N/A 1.368±0.00 N/A N/A 0.272±0.00 N/A N/A 1.545±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JB CIL_0006JB_0002 CGP 5:100679484-100798598
CIL_000820 CIL_000820_0002 VISTA 5:100731954-101333223
CIL_0006JA CIL_0006JA_0002 CGP 5:100762145-100804471

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000724 IEA double-strand break repair via homologous recombination
GO:0003676 IEA nucleic acid binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0006259 ISO DNA metabolic process
GO:0017116 ISO single-stranded DNA-dependent ATP-dependent DNA helicase activity
GO:0017117 ISO single-stranded DNA-dependent ATP-dependent DNA helicase complex
GO:0032508 ISO DNA duplex unwinding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079818 helq helicase, POLQ-like protein_coding Danio_rerio
ENSG00000163312 HELQ helicase, POLQ-like protein_coding Homo_sapiens

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