C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain binding protein 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036206 Sh3bp4 10090 + 1:89070415-89155068 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066279 Sh3bp4-001 89070415-89155068 protein_coding
  ENSMUST00000123745 Sh3bp4-002 89070453-89112860 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066279
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066279 13.183±2.44 7.666±0.89 5.539±0.27 6.606±2.37 10.781±1.83 9.682±0.99 3.175±0.64 6.754±0.72 0.390±0.23 18.630±1.09 0.737±0.11 16.327±4.05 5.377±1.80 1.003±0.38

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004RR CIL_0004RR_0003 CGP 1:88673125-89155068
CIL_0003R3 CIL_0003R3_0002 CGP 1:89070415-89897617

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005092 ISS GDP-dissociation inhibitor activity
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005905 IEA coated pit
GO:0006897 IEA endocytosis
GO:0008285 ISS negative regulation of cell proliferation
GO:0010508 ISS positive regulation of autophagy
GO:0017016 IEA Ras GTPase binding
GO:0030308 ISS negative regulation of cell growth
GO:0031410 IEA cytoplasmic vesicle
GO:0032007 ISS negative regulation of TOR signaling
GO:0034260 ISS negative regulation of GTPase activity
GO:0042802 IEA identical protein binding
GO:0050790 ISS regulation of catalytic activity
GO:0061462 ISS protein localization to lysosome
GO:0070062 IEA extracellular vesicular exosome
GO:0071230 ISS cellular response to amino acid stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020000 sh3bp4a SH3-domain binding protein 4a protein_coding Danio_rerio
ENSDARG00000030104 sh3bp4 SH3-domain binding protein 4 protein_coding Danio_rerio
ENSG00000130147 SH3BP4 SH3-domain binding protein 4 protein_coding Homo_sapiens

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