C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3-domain binding protein 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000130147 SH3BP4 9606 + 2:234951973-235055714 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344528 SH3BP4-003 234978703-235055648 protein_coding
  ENST00000392011 SH3BP4-001 234951973-235055714 protein_coding
  ENST00000409212 SH3BP4-002 234978685-235055648 protein_coding
  ENST00000416021 SH3BP4-005 234952076-235041135 protein_coding
  ENST00000444916 SH3BP4-007 234978705-235040937 protein_coding
  ENST00000446904 SH3BP4-008 234981624-235041288 protein_coding
  ENST00000454947 SH3BP4-009 234994840-235040942 protein_coding
  ENST00000462602 SH3BP4-011 234981634-235008594 processed_transcript
  ENST00000484097 SH3BP4-004 234952035-234953190 processed_transcript
  ENST00000489601 SH3BP4-006 234978700-234979898 processed_transcript
  ENST00000493436 SH3BP4-010 234994524-234995993 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000344528ENST00000392011ENST00000409212
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000344528 4.230±0.00 1.271±0.00 2.015±0.00 2.192±0.00 1.794±0.00 1.646±0.00 9.534±0.00 2.215±1.20 N/A 2.141±0.00 N/A N/A N/A
ENST00000392011 4.234±0.00 2.394±0.00 1.639±0.88 N/A 2.174±0.00 0.804±0.14 N/A 2.379±0.00 3.175±2.22 N/A 9.920±6.67 19.857±8.05 6.683±5.36
ENST00000409212 N/A N/A N/A 0.997±0.25 N/A N/A N/A N/A 0.648±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004RR CIL_0004RR_0002 CGP 2:234493041-235055714
CIL_0003R3 CIL_0003R3_0001 CGP 2:234951973-236131800

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005092 IMP GDP-dissociation inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005905 IEA coated pit
GO:0006897 IEA endocytosis
GO:0008285 IMP negative regulation of cell proliferation
GO:0010508 IMP positive regulation of autophagy
GO:0017016 IPI Ras GTPase binding
GO:0030308 IMP negative regulation of cell growth
GO:0031410 IEA cytoplasmic vesicle
GO:0032007 IMP negative regulation of TOR signaling
GO:0034260 IDA negative regulation of GTPase activity
GO:0042802 IPI identical protein binding
GO:0050790 IMP regulation of catalytic activity
GO:0061462 IMP protein localization to lysosome
GO:0070062 IDA extracellular vesicular exosome
GO:0071230 IMP cellular response to amino acid stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020000 sh3bp4a SH3-domain binding protein 4a protein_coding Danio_rerio
ENSDARG00000030104 sh3bp4 SH3-domain binding protein 4 protein_coding Danio_rerio
ENSMUSG00000036206 Sh3bp4 SH3-domain binding protein 4 protein_coding Mus_musculus

Loading