C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: CCR4-NOT transcription complex, subunit 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036550 Cnot1 10090 - 8:95719451-95807462 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000068452 Cnot1-201 95719451-95807462 protein_coding
  ENSMUST00000098473 Cnot1-202 95719451-95807462 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000068452ENSMUST00000098473
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000068452 N/A N/A N/A 2.439±0.58 N/A 3.448±0.00 N/A N/A N/A N/A N/A 3.996±2.03 4.919±0.40 N/A
ENSMUST00000098473 4.606±0.95 2.704±1.12 4.790±0.96 8.028±6.20 5.226±1.27 5.945±3.10 3.010±0.66 5.142±1.67 4.371±2.17 3.871±0.95 3.552±1.70 8.104±6.33 16.131±5.69 12.543±3.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Z0 CIL_0008Z0_0002 VISTA 8:95126508-95728314
CIL_0004IZ CIL_0004IZ_0002 CGP 8:95715915-95807462

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0001829 IMP trophectodermal cell differentiation
GO:0004535 IEA poly(A)-specific ribonuclease activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IEA nucleus
GO:0005778 IEA peroxisomal membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006417 IEA regulation of translation
GO:0010606 IEA positive regulation of cytoplasmic mRNA processing body assembly
GO:0016020 IEA membrane
GO:0030014 IEA CCR4-NOT complex
GO:0030331 IEA estrogen receptor binding
GO:0031047 IEA gene silencing by RNA
GO:0033147 IEA negative regulation of intracellular estrogen receptor signaling pathway
GO:0042974 IEA retinoic acid receptor binding
GO:0044822 IEA poly(A) RNA binding
GO:0048387 IEA negative regulation of retinoic acid receptor signaling pathway
GO:0060213 IEA positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
GO:0090503 IEA RNA phosphodiester bond hydrolysis, exonucleolytic
GO:1900153 IEA positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:2000036 IEA regulation of stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004174 cnot1 CCR4-NOT transcription complex, subunit 1 protein_coding Danio_rerio
ENSG00000125107 CNOT1 CCR4-NOT transcription complex, subunit 1 protein_coding Homo_sapiens

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