C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: amyloid beta (A4) precursor protein-binding, family B, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037032 Apbb1 10090 - 7:105558483-105581653 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000081165 Apbb1-201 105558486-105574402 protein_coding
  ENSMUST00000186814 Apbb1-014 105559468-105567294 retained_intron
  ENSMUST00000186868 Apbb1-009 105567094-105569592 protein_coding
  ENSMUST00000187051 Apbb1-010 105566665-105569273 protein_coding
  ENSMUST00000187057 Apbb1-007 105558818-105568777 protein_coding
  ENSMUST00000187683 Apbb1-011 105566550-105569265 protein_coding
  ENSMUST00000187721 Apbb1-012 105566107-105568963 protein_coding
  ENSMUST00000188001 Apbb1-006 105558487-105568956 retained_intron
  ENSMUST00000188368 Apbb1-008 105558484-105568777 protein_coding
  ENSMUST00000188440 Apbb1-017 105565590-105581192 protein_coding
  ENSMUST00000188726 Apbb1-016 105573968-105581188 protein_coding
  ENSMUST00000189072 Apbb1-004 105558484-105569513 protein_coding
  ENSMUST00000189265 Apbb1-018 105558523-105569292 protein_coding
  ENSMUST00000189378 Apbb1-002 105558503-105581491 protein_coding
  ENSMUST00000190369 Apbb1-005 105558484-105569297 protein_coding
  ENSMUST00000190961 Apbb1-013 105567168-105568670 retained_intron
  ENSMUST00000191011 Apbb1-001 105558483-105581653 protein_coding
  ENSMUST00000191250 Apbb1-015 105559161-105565505 retained_intron
  ENSMUST00000191601 Apbb1-003 105558484-105581278 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000081165ENSMUST00000187057ENSMUST00000188440ENSMUST00000189072ENSMUST00000189265ENSMUST00000189378ENSMUST00000191011ENSMUST00000191250ENSMUST00000191601
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000081165 N/A N/A N/A 38.471±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000187057 N/A 3.521±0.35 N/A N/A 1.493±0.00 2.425±0.17 N/A 1.553±0.00 N/A N/A N/A N/A N/A 4.585±0.49
ENSMUST00000188440 N/A N/A N/A 93.033±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.198±0.00
ENSMUST00000189072 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.488±0.00
ENSMUST00000189265 N/A N/A N/A N/A 3.078±0.00 N/A 33.748±2.18 N/A 0.264±0.14 16.644±1.47 N/A 4.319±0.21 N/A 3.838±1.67
ENSMUST00000189378 1.904±0.57 N/A 7.889±0.09 N/A N/A N/A N/A 1.840±0.62 0.514±0.26 N/A 1.185±0.45 2.177±0.89 4.816±2.85 N/A
ENSMUST00000191011 2.102±0.88 N/A 6.588±0.04 10.391±1.04 1.029±0.03 1.456±0.36 11.062±1.56 1.616±0.45 0.305±0.14 10.585±1.73 1.613±0.57 2.667±1.62 5.466±2.38 1.154±0.26
ENSMUST00000191250 N/A N/A N/A N/A N/A N/A 50.150±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000191601 2.197±1.15 6.668±0.90 N/A 65.917±7.07 3.490±0.77 5.587±1.53 5.442±0.00 3.736±0.87 0.288±0.32 21.428±3.33 0.876±0.02 7.325±2.04 2.780±0.76 1.178±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004AE CIL_0004AE_0002 CGP 7:105554360-105581653
CIL_0004N8 CIL_0004N8_0002 CGP 7:105558483-105600116

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001540 ISS beta-amyloid binding
GO:0001764 IGI neuron migration
GO:0003682 IEA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006302 IMP double-strand break repair
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007050 IDA cell cycle arrest
GO:0007411 IGI axon guidance
GO:0008134 IDA transcription factor binding
GO:0008542 IMP visual learning
GO:0030027 ISS lamellipodium
GO:0030048 NAS actin filament-based movement
GO:0030198 IGI extracellular matrix organization
GO:0030308 IDA negative regulation of cell growth
GO:0030426 ISS growth cone
GO:0035035 NAS histone acetyltransferase binding
GO:0042393 IEA histone binding
GO:0043065 ISS positive regulation of apoptotic process
GO:0043967 ISS histone H4 acetylation
GO:0045202 ISS synapse
GO:0045665 IMP negative regulation of neuron differentiation
GO:0045739 IMP positive regulation of DNA repair
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0050760 IDA negative regulation of thymidylate synthase biosynthetic process
GO:0050821 NAS protein stabilization
GO:0070064 IEA proline-rich region binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076560 apbb1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) protein_coding Danio_rerio
ENSG00000166313 APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) protein_coding Homo_sapiens

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