C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000045270 Cbfa2t2-002 ENSMUSG00000038533 10090 + 2:154436495-154539356 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045270
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045270 4.116±1.41 4.467±0.57 8.391±3.42 1.854±0.67 3.948±0.00 2.779±0.55 3.416±0.84 1.938±0.64 2.670±0.29 1.821±0.22 3.490±0.65 3.450±1.69 2.724±0.93

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006PI CIL_0006PI_0002 CGP 2:154376313-154539356
CIL_00051Z CIL_00051Z_0002 CGP 2:154436481-154558890

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0010976 IEA positive regulation of neuron projection development
GO:0010977 ISS negative regulation of neuron projection development
GO:0030855 IMP epithelial cell differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000342704 CBFA2T2-009 protein_coding Homo_sapiens 0 2381
ENST00000344201 CBFA2T2-005 protein_coding Homo_sapiens 0 867
ENST00000346541 CBFA2T2-201 protein_coding Homo_sapiens 0 2318
ENST00000359606 CBFA2T2-007 protein_coding Homo_sapiens 0 2318
ENST00000375279 CBFA2T2-003 protein_coding Homo_sapiens 0 2318
ENST00000397800 CBFA2T2-202 protein_coding Homo_sapiens 0 2318
ENST00000471007 CBFA2T2-002 processed_transcript Homo_sapiens 0 593
ENST00000491618 CBFA2T2-006 processed_transcript Homo_sapiens 0 702
ENST00000492345 CBFA2T2-004 protein_coding Homo_sapiens 0 2318
ENST00000543126 CBFA2T2-203 protein_coding Homo_sapiens 0 701

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