C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulator of telomere elongation helicase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038685 Rtel1 10090 + 2:181319739-181356616 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048608 Rtel1-005 181319785-181356616 protein_coding
  ENSMUST00000054622 Rtel1-001 181319762-181356616 protein_coding
  ENSMUST00000098971 Rtel1-003 181319739-181356616 protein_coding
  ENSMUST00000108814 Rtel1-007 181319785-181356578 protein_coding
  ENSMUST00000108815 Rtel1-006 181319785-181356616 protein_coding
  ENSMUST00000124149 Rtel1-021 181355694-181356615 processed_transcript
  ENSMUST00000125233 Rtel1-012 181349455-181349955 retained_intron
  ENSMUST00000126842 Rtel1-011 181339111-181347031 retained_intron
  ENSMUST00000130772 Rtel1-015 181352082-181355552 retained_intron
  ENSMUST00000130935 Rtel1-013 181350018-181352063 retained_intron
  ENSMUST00000133856 Rtel1-018 181355765-181356614 protein_coding
  ENSMUST00000134651 Rtel1-020 181355970-181356616 protein_coding
  ENSMUST00000137700 Rtel1-019 181355970-181356616 protein_coding
  ENSMUST00000139601 Rtel1-017 181355203-181356017 retained_intron
  ENSMUST00000139608 Rtel1-004 181319762-181356578 retained_intron
  ENSMUST00000144648 Rtel1-014 181350128-181351155 retained_intron
  ENSMUST00000146273 Rtel1-002 181319753-181347458 retained_intron
  ENSMUST00000147266 Rtel1-016 181354400-181355813 processed_transcript
  ENSMUST00000148252 Rtel1-008 181328617-181356616 protein_coding
  ENSMUST00000153112 Rtel1-009 181319963-181323694 protein_coding
  ENSMUST00000184751 Rtel1-010 181335936-181347048 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054622ENSMUST00000098971ENSMUST00000108814ENSMUST00000108815ENSMUST00000124149ENSMUST00000130772ENSMUST00000139601ENSMUST00000139608ENSMUST00000148252
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054622 3.602±0.55 2.034±0.86 2.528±0.30 4.015±1.15 2.606±1.12 1.353±0.31 1.015±0.44 1.390±0.36 3.253±2.52 1.407±0.53 0.850±0.19 2.911±0.97 2.968±0.85 4.810±1.04
ENSMUST00000098971 2.176±0.00 1.415±0.31 1.842±0.09 2.655±0.67 2.155±0.16 1.211±0.00 0.831±0.24 1.436±0.18 2.330±1.19 1.712±0.34 0.850±0.33 2.358±0.54 1.853±0.44 3.307±0.46
ENSMUST00000108814 1.810±0.05 1.885±0.36 N/A N/A 1.932±0.67 1.307±0.16 N/A 1.740±0.46 1.959±0.35 1.632±0.38 N/A 2.807±0.63 1.239±0.00 N/A
ENSMUST00000108815 2.383±0.00 N/A N/A N/A N/A N/A N/A N/A 1.967±0.00 N/A 0.644±0.18 2.457±0.29 N/A 2.653±1.06
ENSMUST00000124149 N/A N/A N/A N/A 12.231±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000130772 6.055±0.24 N/A 5.076±0.39 5.505±2.86 N/A N/A 1.614±0.05 N/A 3.106±0.00 3.885±0.19 1.857±0.18 3.757±0.48 4.457±1.38 1.867±0.00
ENSMUST00000139601 N/A 7.307±0.00 N/A N/A 11.383±0.00 8.471±0.40 N/A 9.620±0.00 N/A N/A N/A 21.274±2.87 17.845±0.00 N/A
ENSMUST00000139608 2.336±0.45 1.138±0.33 1.663±0.00 2.701±0.80 1.981±0.69 1.978±0.37 0.468±0.00 N/A 1.919±0.72 1.564±0.00 0.557±0.15 2.636±0.73 2.083±1.01 2.135±0.16
ENSMUST00000148252 N/A 2.263±0.38 N/A N/A N/A 1.372±0.16 N/A N/A 0.805±0.00 N/A N/A 2.922±0.51 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003U1 CIL_0003U1_0002 CGP 2:181306459-181356616

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000723 IMP telomere maintenance
GO:0003677 IEA DNA binding
GO:0004003 ISS ATP-dependent DNA helicase activity
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005634 IDA nucleus
GO:0006200 IEA ATP catabolic process
GO:0006281 IEA DNA repair
GO:0010569 ISS regulation of double-strand break repair via homologous recombination
GO:0032508 IEA DNA duplex unwinding
GO:0046872 IEA metal ion binding
GO:0051539 IEA 4 iron, 4 sulfur cluster binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035074 rtel1 regulator of telomere elongation helicase 1 protein_coding Danio_rerio
ENSG00000258366 RTEL1 regulator of telomere elongation helicase 1 protein_coding Homo_sapiens

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