C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM homeobox transcription factor 1 beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038765 Lmx1b 10090 - 2:33560965-33640511 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000041730 Lmx1b-001 33560965-33640511 protein_coding
  ENSMUST00000137559 Lmx1b-002 33567156-33632283 processed_transcript
  ENSMUST00000176067 Lmx1b-003 33564325-33640480 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000041730ENSMUST00000137559ENSMUST00000176067
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000041730 0.006±0.00 0.010±0.00 0.035±0.00 1.795±2.23 2.981±1.38 0.035±0.02 0.020±0.00 0.403±0.19 0.017±0.02 0.052±0.00 0.040±0.01 0.018±0.01 0.223±0.27 0.048±0.02
ENSMUST00000137559 N/A N/A N/A N/A N/A 0.227±0.00 N/A N/A 0.042±0.00 N/A N/A N/A 0.636±0.00 N/A
ENSMUST00000176067 N/A 0.020±0.00 N/A 0.155±0.00 N/A 0.075±0.02 0.086±0.00 N/A 0.014±0.01 N/A 0.053±0.00 N/A 0.203±0.13 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002XT CIL_0002XT_0002 CGP 2:33450287-33640511
CIL_0008M0 CIL_0008M0_0002 VISTA 2:33488143-34090459
CIL_0002XW CIL_0002XW_0002 CGP 2:33560965-33887946

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IMP neuron migration
GO:0002930 IMP trabecular meshwork development
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0008270 IEA zinc ion binding
GO:0008283 IMP cell proliferation
GO:0009953 IEP dorsal/ventral pattern formation
GO:0010468 IMP regulation of gene expression
GO:0021587 IMP cerebellum morphogenesis
GO:0021954 IMP central nervous system neuron development
GO:0030182 IMP neuron differentiation
GO:0030199 IMP collagen fibril organization
GO:0030326 NAS embryonic limb morphogenesis
GO:0030901 IMP midbrain development
GO:0035108 IMP limb morphogenesis
GO:0035265 IMP organ growth
GO:0043010 IMP camera-type eye development
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0071542 IMP dopaminergic neuron differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019306 lmx1ba LIM homeobox transcription factor 1, beta a protein_coding Danio_rerio
ENSDARG00000068365 lmx1bb LIM homeobox transcription factor 1, beta b protein_coding Danio_rerio
ENSG00000136944 LMX1B LIM homeobox transcription factor 1, beta protein_coding Homo_sapiens

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