C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prohibitin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038845 Phb 10090 + 11:95666957-95680773 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000036374 Phb-002 95667064-95679708 protein_coding
  ENSMUST00000123001 Phb-005 95671450-95676060 processed_transcript
  ENSMUST00000123071 Phb-004 95667000-95671642 processed_transcript
  ENSMUST00000125172 Phb-001 95666957-95680773 protein_coding
  ENSMUST00000127031 Phb-003 95667010-95668613 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000036374ENSMUST00000123071ENSMUST00000125172
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000036374 33.596±7.25 36.776±3.61 18.100±0.00 34.412±0.00 24.610±8.30 18.541±2.68 48.943±13.20 46.050±9.90 54.442±3.78 10.527±2.16 39.879±2.91 38.713±12.44 31.770±20.04 N/A
ENSMUST00000123071 N/A N/A 37.798±4.24 28.887±0.00 N/A N/A N/A N/A 111.450±8.66 N/A N/A 62.891±33.23 66.000±35.64 21.237±0.00
ENSMUST00000125172 26.747±3.99 19.504±1.00 29.459±1.03 32.868±4.60 16.919±4.17 17.776±2.37 41.047±3.41 49.108±4.38 29.538±14.36 13.577±1.61 35.659±0.96 24.154±7.47 34.778±17.20 22.109±11.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004S8 CIL_0004S8_0002 CGP 11:95666957-95835115

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001541 IEA ovarian follicle development
GO:0001552 IEA ovarian follicle atresia
GO:0001649 IEA osteoblast differentiation
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 IEA nucleoplasm
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005743 IDA mitochondrial inner membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0008285 IEA negative regulation of cell proliferation
GO:0010944 IEA negative regulation of transcription by competitive promoter binding
GO:0016020 IEA membrane
GO:0016575 IEA histone deacetylation
GO:0019899 IEA enzyme binding
GO:0030061 IEA mitochondrial crista
GO:0030308 IEA negative regulation of cell growth
GO:0031100 IEA organ regeneration
GO:0031315 IEA extrinsic component of mitochondrial outer membrane
GO:0034097 IEA response to cytokine
GO:0035902 IEA response to immobilization stress
GO:0042493 IEA response to drug
GO:0042826 IEA histone deacetylase binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0043434 IEA response to peptide hormone
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045471 IEA response to ethanol
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0050847 IEA progesterone receptor signaling pathway
GO:0060766 IEA negative regulation of androgen receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome
GO:0071354 IEA cellular response to interleukin-6
GO:0071897 IMP DNA biosynthetic process
GO:2000323 IEA negative regulation of glucocorticoid receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057414 phb prohibitin protein_coding Danio_rerio
ENSG00000167085 PHB prohibitin protein_coding Homo_sapiens

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