C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: isoprenylcysteine carboxyl methyltransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039662 Icmt 10090 + 4:152297227-152307121 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000048892 Icmt-001 152297227-152307121 protein_coding
  ENSMUST00000125617 Icmt-003 152297656-152300754 processed_transcript
  ENSMUST00000134242 Icmt-004 152305387-152307068 processed_transcript
  ENSMUST00000151372 Icmt-002 152297304-152307120 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048892ENSMUST00000151372
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048892 13.670±2.48 33.658±1.20 12.467±0.71 4.176±0.56 10.800±3.52 17.698±1.75 10.646±0.98 13.435±0.62 6.073±2.09 17.587±1.21 6.986±0.84 17.928±4.90 4.729±0.99 22.243±6.36
ENSMUST00000151372 3.173±0.97 5.262±0.15 N/A 2.902±0.20 3.501±0.54 3.839±0.69 N/A 2.408±0.38 1.412±0.40 3.995±0.48 1.311±0.00 3.323±0.66 1.538±0.98 2.531±0.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003D3 CIL_0003D3_0002 CGP 4:152297227-152318993

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0004671 IMP protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0005783 IEA endoplasmic reticulum
GO:0006479 IMP protein methylation
GO:0006481 IMP C-terminal protein methylation
GO:0008104 IMP protein localization
GO:0008140 IMP cAMP response element binding protein binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0016021 IEA integral component of membrane
GO:0035264 IMP multicellular organism growth
GO:0046578 IGI regulation of Ras protein signal transduction
GO:2001141 IMP regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020241 icmt isoprenylcysteine carboxyl methyltransferase protein_coding Danio_rerio
ENSG00000116237 ICMT isoprenylcysteine carboxyl methyltransferase protein_coding Homo_sapiens

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