C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: isoprenylcysteine carboxyl methyltransferase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000151372 Icmt-002 ENSMUSG00000039662 10090 + 4:152297304-152307120 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000151372
Transcript ID Adipose Adrenal Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000151372 3.173±0.97 5.262±0.15 2.902±0.20 3.501±0.54 3.839±0.69 2.408±0.38 1.412±0.40 3.995±0.48 1.311±0.00 3.323±0.66 1.538±0.98 2.531±0.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003D3 CIL_0003D3_0002 CGP 4:152297227-152318993

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0004671 IMP protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0006479 IMP protein methylation
GO:0006481 IMP C-terminal protein methylation
GO:0008104 IMP protein localization
GO:0008140 IMP cAMP response element binding protein binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0035264 IMP multicellular organism growth
GO:0046578 IGI regulation of Ras protein signal transduction
GO:2001141 IMP regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000343813 ICMT-001 protein_coding Homo_sapiens 0 730
ENST00000377939 RNF207-001 protein_coding Homo_sapiens 3e-28 132
ENST00000474756 ICMT-006 nonsense_mediated_decay Homo_sapiens 0 532
ENST00000489498 ICMT-002 nonsense_mediated_decay Homo_sapiens 0 1286

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