C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: isoprenylcysteine carboxyl methyltransferase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000048892 Icmt-001 ENSMUSG00000039662 10090 + 4:152297227-152307121 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000048892
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000048892 13.670±2.48 33.658±1.20 12.467±0.71 4.176±0.56 10.800±3.52 17.698±1.75 10.646±0.98 13.435±0.62 6.073±2.09 17.587±1.21 6.986±0.84 17.928±4.90 4.729±0.99 22.243±6.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003D3 CIL_0003D3_0002 CGP 4:152297227-152318993

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0001889 IMP liver development
GO:0004671 IMP protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
GO:0005783 IEA endoplasmic reticulum
GO:0006479 IMP protein methylation
GO:0006481 IMP C-terminal protein methylation
GO:0008104 IMP protein localization
GO:0008140 IMP cAMP response element binding protein binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0016021 IEA integral component of membrane
GO:0035264 IMP multicellular organism growth
GO:0046578 IGI regulation of Ras protein signal transduction
GO:2001141 IMP regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000343813 ICMT-001 protein_coding Homo_sapiens 0 1162
ENST00000377939 RNF207-001 protein_coding Homo_sapiens 9e-29 134
ENST00000474756 ICMT-006 nonsense_mediated_decay Homo_sapiens 0 532
ENST00000489498 ICMT-002 nonsense_mediated_decay Homo_sapiens 0 730

Loading