C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: endonuclease V
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039850 Endov 10090 + 11:119491347-119511437 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064513 Endov-011 119499511-119505962 protein_coding
  ENSMUST00000106244 Endov-001 119491347-119511423 protein_coding
  ENSMUST00000106245 Endov-003 119491630-119511437 protein_coding
  ENSMUST00000129327 Endov-005 119491389-119507751 protein_coding
  ENSMUST00000132015 Endov-009 119501978-119507389 retained_intron
  ENSMUST00000134873 Endov-004 119491785-119502827 processed_transcript
  ENSMUST00000140323 Endov-010 119491426-119507379 protein_coding
  ENSMUST00000143670 Endov-008 119491676-119500817 retained_intron
  ENSMUST00000143817 Endov-002 119491375-119509579 nonsense_mediated_decay
  ENSMUST00000153204 Endov-006 119491374-119507691 nonsense_mediated_decay
  ENSMUST00000154370 Endov-007 119491551-119505121 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064513ENSMUST00000106244ENSMUST00000106245ENSMUST00000129327ENSMUST00000140323ENSMUST00000143670ENSMUST00000143817ENSMUST00000153204
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064513 N/A N/A N/A N/A N/A N/A N/A N/A 1.292±0.20 N/A N/A N/A N/A N/A
ENSMUST00000106244 2.647±0.57 1.561±0.77 2.369±0.15 4.119±1.72 1.691±0.48 2.158±0.42 1.101±0.09 1.122±0.29 1.072±0.43 2.036±0.23 0.389±0.10 2.125±0.90 0.494±0.15 1.292±0.67
ENSMUST00000106245 1.162±0.69 1.370±0.55 2.936±0.77 5.677±0.32 1.815±0.43 2.170±0.38 0.322±0.00 1.155±0.56 0.737±0.00 2.228±0.63 0.380±0.00 2.832±1.22 0.582±0.00 1.060±0.70
ENSMUST00000129327 3.026±0.32 3.453±0.53 N/A N/A 3.388±0.00 5.707±2.08 N/A 2.148±0.35 1.921±0.43 N/A 1.000±0.08 6.675±1.30 1.204±0.17 2.456±0.00
ENSMUST00000140323 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.481±0.00 9.452±0.00 1.998±0.15 1.455±0.00
ENSMUST00000143670 N/A N/A N/A N/A N/A N/A N/A N/A 3.135±0.00 N/A N/A N/A 1.597±0.00 N/A
ENSMUST00000143817 1.801±0.85 2.248±0.70 1.308±0.02 4.963±0.00 1.956±0.40 2.790±0.52 0.693±0.14 1.190±0.32 0.673±0.20 1.625±0.11 0.664±0.11 2.795±0.79 0.552±0.17 2.091±0.34
ENSMUST00000153204 N/A N/A N/A 8.394±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002LC CIL_0002LC_0002 CGP 11:119393100-119511437
CIL_00042I CIL_00042I_0002 CGP 11:119491347-119547753

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0000737 IDA DNA catabolic process, endonucleolytic
GO:0003727 ISS single-stranded RNA binding
GO:0004519 IEA endonuclease activity
GO:0005730 ISS nucleolus
GO:0005737 ISS cytoplasm
GO:0006281 IEA DNA repair
GO:0016888 IDA endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:0016891 ISS endoribonuclease activity, producing 5'-phosphomonoesters
GO:0043566 ISS structure-specific DNA binding
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis
GO:0090502 IEA RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000173818 ENDOV endonuclease V protein_coding Homo_sapiens

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