C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain containing, family G (with RhoGef domain) member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040624 Plekhg1 10090 + 10:3740364-3967303 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042438 Plekhg1-201 3872667-3967303 protein_coding
  ENSMUST00000120274 Plekhg1-001 3740364-3967303 protein_coding
  ENSMUST00000131525 Plekhg1-006 3903582-3919362 retained_intron
  ENSMUST00000136671 Plekhg1-002 3872667-3964549 protein_coding
  ENSMUST00000137111 Plekhg1-005 3740665-3938577 retained_intron
  ENSMUST00000141367 Plekhg1-007 3957891-3963526 nonsense_mediated_decay
  ENSMUST00000144543 Plekhg1-004 3740378-3938595 retained_intron
  ENSMUST00000154727 Plekhg1-003 3903586-3967298 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042438ENSMUST00000120274ENSMUST00000136671ENSMUST00000154727
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042438 N/A N/A 1.560±0.24 1.250±0.00 2.677±0.00 N/A 0.343±0.00 N/A 0.140±0.04 N/A 0.404±0.19 3.639±0.06 4.136±1.73 0.875±0.23
ENSMUST00000120274 2.345±0.04 0.630±0.24 1.710±0.09 1.631±0.59 1.098±0.34 0.891±0.32 1.149±0.41 1.460±0.52 0.622±0.30 2.843±0.24 0.298±0.17 0.882±0.26 3.652±1.98 0.560±0.33
ENSMUST00000136671 0.887±0.01 0.320±0.04 N/A N/A 1.106±0.17 0.688±0.45 0.277±0.02 0.568±0.05 0.164±0.02 1.023±0.23 N/A 2.083±0.67 N/A 0.517±0.09
ENSMUST00000154727 0.653±0.11 N/A N/A 0.488±0.00 0.462±0.10 N/A 0.364±0.05 0.473±0.00 0.211±0.08 0.983±0.13 0.150±0.03 0.856±0.26 N/A 0.432±0.31

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005OK CIL_0005OK_0002 CGP 10:3540240-3967303
CIL_0005ED CIL_0005ED_0002 CGP 10:3740364-4167081

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005575 ND cellular_component
GO:0008150 ND biological_process
GO:0032321 IEA positive regulation of Rho GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063484 PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 protein_coding Danio_rerio
ENSG00000120278 PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 protein_coding Homo_sapiens

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