C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: MyoD family inhibitor domain containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041390 Mdfic 10090 + 6:15720661-15802169 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000101663 Mdfic-001 15720661-15802165 protein_coding
  ENSMUST00000120512 Mdfic-004 15721087-15800808 protein_coding
  ENSMUST00000125326 Mdfic-003 15720721-15773304 protein_coding
  ENSMUST00000128849 Mdfic-005 15727799-15770349 protein_coding
  ENSMUST00000140516 Mdfic-002 15720703-15771235 nonsense_mediated_decay
  ENSMUST00000189359 Mdfic-201 15720661-15802169 protein_coding
  ENSMUST00000190255 Mdfic-006 15720661-15802165 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000101663ENSMUST00000120512ENSMUST00000125326ENSMUST00000128849ENSMUST00000189359
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000101663 6.889±1.09 7.322±0.57 2.386±0.83 1.023±0.21 5.312±2.95 2.078±0.79 1.099±0.47 1.826±0.34 1.752±0.51 8.871±4.24 0.639±0.16 13.694±5.74 1.469±0.57 0.115±0.05
ENSMUST00000120512 4.700±0.96 15.544±3.41 4.856±1.31 0.852±0.11 5.520±2.12 3.834±0.75 2.176±0.16 3.389±0.95 1.326±0.54 6.975±0.05 0.764±0.00 12.909±7.00 3.814±2.25 0.189±0.02
ENSMUST00000125326 N/A N/A N/A N/A N/A 0.899±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000128849 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.369±0.07
ENSMUST00000189359 N/A 8.476±1.40 5.618±2.61 N/A 2.388±1.31 1.802±0.47 0.596±0.10 1.705±0.22 1.672±0.47 4.630±0.16 N/A 14.755±6.66 2.093±0.63 0.113±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000411 CIL_000411_0002 CGP 6:14901349-15802169
CIL_0007K6 CIL_0007K6_0003 UCNEbase 6:14952789-16992593
CIL_0008OY CIL_0008OY_0002 VISTA 6:15135024-15737812
CIL_000814 CIL_000814_0002 VISTA 6:15186410-15787741
CIL_000894 CIL_000894_0002 VISTA 6:15200356-15801750
CIL_00094G CIL_00094G_0002 VISTA 6:15310145-15910753
CIL_000410 CIL_000410_0002 CGP 6:15720661-16898441

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005730 IDA nucleolus
GO:0005737 ISS cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0006351 IEA transcription, DNA-templated
GO:0007257 IEA activation of JUN kinase activity
GO:0008134 ISS transcription factor binding
GO:0030111 IEA regulation of Wnt signaling pathway
GO:0030332 ISS cyclin binding
GO:0030957 ISS Tat protein binding
GO:0042308 IDA negative regulation of protein import into nucleus
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0050434 ISS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074223 MDFIC (1 of 2) MyoD family inhibitor domain containing protein_coding Danio_rerio
ENSDARG00000095284 MDFIC (2 of 2) MyoD family inhibitor domain containing protein_coding Danio_rerio
ENSG00000135272 MDFIC MyoD family inhibitor domain containing protein_coding Homo_sapiens

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