C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 5B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000112198 Kdm5b-003 ENSMUSG00000042207 10090 + 1:134560192-134631522 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000112198
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000112198 3.678±1.14 3.276±0.55 2.324±0.20 12.915±3.45 4.931±1.87 3.176±0.63 1.395±0.43 1.558±0.45 1.317±0.95 2.153±0.59 0.949±0.15 8.872±2.46 8.623±4.43 15.693±3.88

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IDA histone demethylase activity (H3-K4 specific)
GO:0034647 ISS histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 ISS histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 ISS histone H3-K4 demethylation
GO:0042752 NAS regulation of circadian rhythm
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000058729 kdm5ba-201 protein_coding Danio_rerio 0 691
ENSDART00000135443 kdm5ba-001 protein_coding Danio_rerio 0 691
ENST00000235790 KDM5B-002 protein_coding Homo_sapiens 0 4883
ENST00000367264 KDM5B-003 protein_coding Homo_sapiens 0 4553
ENST00000367265 KDM5B-001 protein_coding Homo_sapiens 0 5616
ENST00000456180 KDM5B-007 processed_transcript Homo_sapiens 0 669
ENST00000470573 KDM5B-006 processed_transcript Homo_sapiens 0 363
ENST00000472822 KDM5B-005 retained_intron Homo_sapiens 0 1892
ENST00000491153 KDM5B-009 retained_intron Homo_sapiens 0 444
ENST00000498276 KDM5B-008 retained_intron Homo_sapiens 0 385
ENST00000602511 KDM5B-010 nonsense_mediated_decay Homo_sapiens 0 409

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