C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: reelin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042453 Reln 10090 - 5:21884454-22344702 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062372 Reln-002 21885250-22344690 protein_coding
  ENSMUST00000159741 Reln-012 22047524-22048753 retained_intron
  ENSMUST00000159768 Reln-009 21898724-21932719 retained_intron
  ENSMUST00000160707 Reln-006 22224874-22344690 retained_intron
  ENSMUST00000160791 Reln-013 21884895-21896068 processed_transcript
  ENSMUST00000161353 Reln-010 21976038-22010264 retained_intron
  ENSMUST00000161356 Reln-001 21884454-22344702 protein_coding
  ENSMUST00000161782 Reln-007 22342071-22344702 processed_transcript
  ENSMUST00000162427 Reln-008 22003033-22344690 retained_intron
  ENSMUST00000162622 Reln-005 22170326-22344690 retained_intron
  ENSMUST00000162637 Reln-004 22128073-22344690 retained_intron
  ENSMUST00000162876 Reln-011 22060313-22134669 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000062372ENSMUST00000159768ENSMUST00000160791ENSMUST00000161356ENSMUST00000162622
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000062372 N/A 0.233±0.05 0.777±0.00 N/A 0.489±0.19 0.846±0.23 0.169±0.08 0.172±0.08 5.267±0.19 0.634±0.24 N/A 2.670±0.84 N/A N/A
ENSMUST00000159768 0.207±0.03 0.696±0.22 1.239±0.04 9.269±1.58 N/A 0.573±0.00 0.263±0.02 0.426±0.12 5.626±1.10 N/A N/A N/A 0.071±0.00 0.837±0.09
ENSMUST00000160791 N/A N/A N/A N/A N/A N/A N/A N/A 13.962±0.00 N/A 0.663±0.18 N/A 0.171±0.03 1.115±0.00
ENSMUST00000161356 N/A N/A N/A 8.584±1.30 N/A N/A 0.099±0.00 N/A N/A N/A N/A 1.521±0.29 0.068±0.00 N/A
ENSMUST00000162622 N/A 0.645±0.03 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005C9 CIL_0005C9_0002 CGP 5:21810655-22344702
CIL_00040Z CIL_00040Z_0002 CGP 5:21884454-22550429

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000904 IMP cell morphogenesis involved in differentiation
GO:0001764 IGI neuron migration
GO:0005515 IPI protein binding
GO:0005578 TAS proteinaceous extracellular matrix
GO:0005615 IDA extracellular space
GO:0005737 IDA cytoplasm
GO:0006508 IEA proteolysis
GO:0007155 IEA cell adhesion
GO:0007411 IMP axon guidance
GO:0007417 IMP central nervous system development
GO:0007420 IMP brain development
GO:0007616 IDA long-term memory
GO:0008236 IEA serine-type peptidase activity
GO:0008306 IDA associative learning
GO:0010001 IMP glial cell differentiation
GO:0010468 IMP regulation of gene expression
GO:0010976 IMP positive regulation of neuron projection development
GO:0014068 IDA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016358 IGI dendrite development
GO:0016477 IMP cell migration
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0021511 IMP spinal cord patterning
GO:0021517 IEP ventral spinal cord development
GO:0021766 IDA hippocampus development
GO:0021800 IMP cerebral cortex tangential migration
GO:0021819 IMP layer formation in cerebral cortex
GO:0021987 IMP cerebral cortex development
GO:0030425 IDA dendrite
GO:0030900 IMP forebrain development
GO:0032008 IDA positive regulation of TOR signaling
GO:0032793 IDA positive regulation of CREB transcription factor activity
GO:0035418 IMP protein localization to synapse
GO:0038026 IDA reelin-mediated signaling pathway
GO:0045860 IDA positive regulation of protein kinase activity
GO:0046872 IEA metal ion binding
GO:0048265 IMP response to pain
GO:0050731 IDA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050795 IMP regulation of behavior
GO:0050804 IMP regulation of synaptic transmission
GO:0051057 IDA positive regulation of small GTPase mediated signal transduction
GO:0051968 IDA positive regulation of synaptic transmission, glutamatergic
GO:0061003 IMP positive regulation of dendritic spine morphogenesis
GO:0061098 IDA positive regulation of protein tyrosine kinase activity
GO:0070325 IPI lipoprotein particle receptor binding
GO:0070326 IPI very-low-density lipoprotein particle receptor binding
GO:0090129 IDA positive regulation of synapse maturation
GO:0097107 IC postsynaptic density assembly
GO:0097114 IMP N-methyl-D-aspartate receptor clustering
GO:0097119 IMP postsynaptic density protein 95 clustering
GO:0097120 IMP receptor localization to synapse
GO:0097477 IMP lateral motor column neuron migration
GO:1900273 IDA positive regulation of long-term synaptic potentiation
GO:1902078 IMP positive regulation of lateral motor column neuron migration
GO:2000310 IMP regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000463 IDA positive regulation of excitatory postsynaptic membrane potential
GO:2000969 IDA positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038188 RELN (1 of 4) reelin protein_coding Danio_rerio
ENSDARG00000077935 relnl reelin, like protein_coding Danio_rerio
ENSG00000189056 RELN reelin protein_coding Homo_sapiens

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