C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: reelin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000189056 RELN 9606 - 7:103471784-103989516 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000343529 RELN-002 103471784-103989516 protein_coding
  ENST00000424685 RELN-201 103471784-103989516 protein_coding
  ENST00000428762 RELN-001 103471784-103989516 protein_coding
  ENST00000429186 RELN-009 103472230-103482948 protein_coding
  ENST00000473457 RELN-006 103627909-103630136 processed_transcript
  ENST00000473945 RELN-008 103481941-103486257 processed_transcript
  ENST00000478148 RELN-007 103523500-103539488 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343529ENST00000424685ENST00000428762ENST00000429186
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343529 0.298±0.00 0.442±0.00 0.044±0.00 2.845±0.00 0.189±0.00 0.373±0.09 0.134±0.08 3.496±3.23 1.671±1.02 0.164±0.00 0.124±0.05 0.207±0.08 0.073±0.07 0.585±0.09
ENST00000424685 N/A N/A 0.043±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.003±0.00 N/A
ENST00000428762 N/A N/A 0.044±0.00 1.324±0.58 0.636±0.00 N/A N/A N/A N/A N/A N/A 0.013±0.00 0.085±0.08 N/A
ENST00000429186 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.021±0.00 0.039±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005C9 CIL_0005C9_0001 CGP 7:103352730-103989516
CIL_00040Z CIL_00040Z_0001 CGP 7:103471784-104208047

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000904 ISS cell morphogenesis involved in differentiation
GO:0001764 ISS neuron migration
GO:0004712 ISS protein serine/threonine/tyrosine kinase activity
GO:0005515 IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 ISS extracellular space
GO:0005737 ISS cytoplasm
GO:0006508 IEA proteolysis
GO:0007155 IEA cell adhesion
GO:0007411 ISS axon guidance
GO:0007417 ISS central nervous system development
GO:0007420 ISS brain development
GO:0007616 IEA long-term memory
GO:0008236 IEA serine-type peptidase activity
GO:0008306 IEA associative learning
GO:0010001 ISS glial cell differentiation
GO:0010468 IEA regulation of gene expression
GO:0010976 ISS positive regulation of neuron projection development
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016358 IEA dendrite development
GO:0016477 IEA cell migration
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0021511 ISS spinal cord patterning
GO:0021517 IEA ventral spinal cord development
GO:0021766 ISS hippocampus development
GO:0021800 ISS cerebral cortex tangential migration
GO:0021819 IEA layer formation in cerebral cortex
GO:0021987 IEA cerebral cortex development
GO:0030425 ISS dendrite
GO:0030900 IEA forebrain development
GO:0032008 IEA positive regulation of TOR signaling
GO:0032793 ISS positive regulation of CREB transcription factor activity
GO:0035418 IEA protein localization to synapse
GO:0038026 ISS reelin-mediated signaling pathway
GO:0045860 ISS positive regulation of protein kinase activity
GO:0046872 IEA metal ion binding
GO:0048265 ISS response to pain
GO:0050731 ISS positive regulation of peptidyl-tyrosine phosphorylation
GO:0050795 ISS regulation of behavior
GO:0050804 ISS regulation of synaptic transmission
GO:0051057 ISS positive regulation of small GTPase mediated signal transduction
GO:0051968 ISS positive regulation of synaptic transmission, glutamatergic
GO:0061003 ISS positive regulation of dendritic spine morphogenesis
GO:0061098 ISS positive regulation of protein tyrosine kinase activity
GO:0070325 ISS lipoprotein particle receptor binding
GO:0070326 ISS very-low-density lipoprotein particle receptor binding
GO:0090129 ISS positive regulation of synapse maturation
GO:0097114 IEA N-methyl-D-aspartate receptor clustering
GO:0097119 IEA postsynaptic density protein 95 clustering
GO:0097120 IEA receptor localization to synapse
GO:0097477 IEA lateral motor column neuron migration
GO:1900273 ISS positive regulation of long-term synaptic potentiation
GO:1902078 IEA positive regulation of lateral motor column neuron migration
GO:2000310 ISS regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential
GO:2000969 ISS positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038188 RELN (1 of 4) reelin protein_coding Danio_rerio
ENSDARG00000077935 relnl reelin, like protein_coding Danio_rerio
ENSMUSG00000042453 Reln reelin protein_coding Mus_musculus

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