C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000043635 Adamts3 10090 - 5:89673841-89883334 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000061427 Adamts3-201 89673841-89883334 protein_coding
  ENSMUST00000163159 Adamts3-202 89673841-89883334 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000061427ENSMUST00000163159
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000061427 1.101±0.70 1.011±0.10 0.546±0.12 1.648±0.56 0.451±0.28 0.509±0.11 0.476±0.28 0.103±0.00 0.224±0.16 0.309±0.07 0.124±0.05 0.660±0.31 0.353±0.29 0.102±0.00
ENSMUST00000163159 N/A 0.300±0.00 N/A N/A N/A 0.348±0.06 N/A 0.128±0.01 0.035±0.01 N/A N/A 0.652±0.25 0.115±0.04 0.046±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000DB CIL_0000DB_0002 CGP 5:89527429-89883334
CIL_0000DC CIL_0000DC_0002 CGP 5:89673841-90224001

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004175 IEA endopeptidase activity
GO:0004222 IEA metalloendopeptidase activity
GO:0005515 IEA protein binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IEA extracellular space
GO:0006508 IEA proteolysis
GO:0008233 IDA peptidase activity
GO:0008270 IEA zinc ion binding
GO:0010573 IEA vascular endothelial growth factor production
GO:0016485 IDA protein processing
GO:0032964 IEA collagen biosynthetic process
GO:0070062 IEA extracellular vesicular exosome
GO:1900748 IEA positive regulation of vascular endothelial growth factor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060127 adamts3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 protein_coding Danio_rerio
ENSG00000156140 ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 protein_coding Homo_sapiens

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