C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific methyltransferase 2D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048154 Kmt2d 10090 - 15:98831669-98871204 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023741 Kmt2d-001 98831672-98871204 protein_coding
  ENSMUST00000178486 Kmt2d-201 98831669-98871183 protein_coding
  ENSMUST00000184363 Kmt2d-002 98854714-98856309 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023741ENSMUST00000178486
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023741 2.819±1.25 5.570±2.02 4.591±2.08 5.939±2.91 4.853±3.48 3.122±1.23 2.022±0.47 2.648±0.80 1.700±0.79 6.651±1.60 3.041±1.35 7.152±4.13 3.918±1.58 2.884±1.08
ENSMUST00000178486 0.950±0.14 N/A 1.184±0.00 N/A 2.808±1.51 3.032±1.47 1.138±0.00 N/A 0.735±0.00 N/A 1.052±0.59 3.071±0.95 1.625±0.67 0.459±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00000J CIL_00000J_0002 CGP 15:98812798-98871204
CIL_00003S CIL_00003S_0002 CGP 15:98831669-98881404

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001555 IMP oocyte growth
GO:0001701 IMP in utero embryonic development
GO:0005634 IEA nucleus
GO:0006342 IMP chromatin silencing
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0008284 IEA positive regulation of cell proliferation
GO:0018024 IEA histone-lysine N-methyltransferase activity
GO:0033148 IEA positive regulation of intracellular estrogen receptor signaling pathway
GO:0035097 IEA histone methyltransferase complex
GO:0043627 IEA response to estrogen
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048477 IMP oogenesis
GO:0051568 IMP histone H3-K4 methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037060 kmt2d lysine (K)-specific methyltransferase 2D protein_coding Danio_rerio
ENSG00000167548 KMT2D lysine (K)-specific methyltransferase 2D protein_coding Homo_sapiens

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