C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: B cell leukemia/lymphoma 11B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048251 Bcl11b 10090 - 12:107910403-108003602 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000066060 Bcl11b-001 107910403-108003602 protein_coding
  ENSMUST00000109887 Bcl11b-002 107915222-108003414 protein_coding
  ENSMUST00000109891 Bcl11b-003 107915222-108003414 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066060ENSMUST00000109887ENSMUST00000109891
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066060 0.065±0.02 0.028±0.01 0.022±0.00 5.356±1.18 2.856±1.49 1.469±0.32 0.112±0.03 0.319±0.06 0.034±0.02 0.428±0.07 0.009±0.00 0.108±0.08 0.020±0.01 0.018±0.01
ENSMUST00000109887 0.068±0.01 0.179±0.05 0.086±0.00 N/A N/A N/A 0.233±0.11 0.862±0.27 0.046±0.03 0.277±0.00 0.024±0.00 0.127±0.05 0.129±0.07 0.070±0.02
ENSMUST00000109891 0.137±0.01 0.141±0.02 0.089±0.00 13.205±1.03 8.054±4.23 3.265±0.69 0.162±0.04 0.673±0.16 0.063±0.04 0.756±0.21 N/A 0.077±0.03 0.116±0.02 0.031±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KT CIL_0007KT_0002 UCNEbase 12:107085268-108123079
CIL_00080U CIL_00080U_0002 VISTA 12:107477918-108078911
CIL_0005H1 CIL_0005H1_0002 CGP 12:107910403-108179314

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003334 IMP keratinocyte development
GO:0003382 IMP epithelial cell morphogenesis
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007409 IMP axonogenesis
GO:0008285 IDA negative regulation of cell proliferation
GO:0009791 IMP post-embryonic development
GO:0010468 IMP regulation of gene expression
GO:0010837 IMP regulation of keratinocyte proliferation
GO:0019216 IMP regulation of lipid metabolic process
GO:0021773 IMP striatal medium spiny neuron differentiation
GO:0021902 IGI commitment of neuronal cell to specific neuron type in forebrain
GO:0021953 IGI central nervous system neuron differentiation
GO:0031077 IMP post-embryonic camera-type eye development
GO:0033077 IMP T cell differentiation in thymus
GO:0033153 IMP T cell receptor V(D)J recombination
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0043066 IMP negative regulation of apoptotic process
GO:0043368 IMP positive T cell selection
GO:0043565 IDA sequence-specific DNA binding
GO:0043588 IMP skin development
GO:0045664 IMP regulation of neuron differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046632 IMP alpha-beta T cell differentiation
GO:0046872 IEA metal ion binding
GO:0048538 IMP thymus development
GO:0071678 IMP olfactory bulb axon guidance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062510 bcl11ba B-cell CLL/lymphoma 11Ba (zinc finger protein) protein_coding Danio_rerio
ENSDARG00000067727 BCL11B (2 of 2) B-cell CLL/lymphoma 11B (zinc finger protein) protein_coding Danio_rerio
ENSG00000127152 BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) protein_coding Homo_sapiens

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