C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: B-cell CLL/lymphoma 11B (zinc finger protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000127152 BCL11B 9606 - 14:99169287-99271524 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345514 BCL11B-002 99169287-99271485 protein_coding
  ENST00000357195 BCL11B-001 99169287-99271228 protein_coding
  ENST00000443726 BCL11B-003 99173961-99271524 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000345514ENST00000357195ENST00000443726
Transcript ID Adrenal Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000345514 N/A 0.484±0.00 0.267±0.00 1.768±0.00 N/A 0.631±0.00 0.405±0.00 N/A 0.107±0.00 N/A N/A
ENST00000357195 2.189±0.00 0.800±0.30 0.250±0.00 N/A N/A 0.445±0.00 1.472±0.12 0.015±0.00 0.495±0.31 0.046±0.02 0.189±0.04
ENST00000443726 N/A N/A N/A N/A 0.048±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KT CIL_0007KT_0001 UCNEbase 14:98137606-99417500
CIL_00080U CIL_00080U_0001 VISTA 14:98699863-99300807
CIL_0005H1 CIL_0005H1_0001 CGP 14:99169287-99480879

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003334 IEA keratinocyte development
GO:0003382 IEA epithelial cell morphogenesis
GO:0003676 IEA nucleic acid binding
GO:0005515 IPI protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007409 IEA axonogenesis
GO:0008285 IEA negative regulation of cell proliferation
GO:0009791 IEA post-embryonic development
GO:0010468 IEA regulation of gene expression
GO:0010837 IEA regulation of keratinocyte proliferation
GO:0019216 IEA regulation of lipid metabolic process
GO:0021773 IEA striatal medium spiny neuron differentiation
GO:0021902 IEA commitment of neuronal cell to specific neuron type in forebrain
GO:0021953 IEA central nervous system neuron differentiation
GO:0031077 IEA post-embryonic camera-type eye development
GO:0033077 IEA T cell differentiation in thymus
GO:0033153 IEA T cell receptor V(D)J recombination
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0043066 IEA negative regulation of apoptotic process
GO:0043368 IEA positive T cell selection
GO:0043565 IEA sequence-specific DNA binding
GO:0043588 IEA skin development
GO:0045664 IEA regulation of neuron differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046632 IEA alpha-beta T cell differentiation
GO:0046872 IEA metal ion binding
GO:0048538 IEA thymus development
GO:0071678 IEA olfactory bulb axon guidance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062510 bcl11ba B-cell CLL/lymphoma 11Ba (zinc finger protein) protein_coding Danio_rerio
ENSDARG00000067727 BCL11B (2 of 2) B-cell CLL/lymphoma 11B (zinc finger protein) protein_coding Danio_rerio
ENSMUSG00000048251 Bcl11b B cell leukemia/lymphoma 11B protein_coding Mus_musculus

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