C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: B cell leukemia/lymphoma 11B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000066060 Bcl11b-001 ENSMUSG00000048251 10090 - 12:107910403-108003602 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000066060
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000066060 0.065±0.02 0.028±0.01 0.022±0.00 5.356±1.18 2.856±1.49 1.469±0.32 0.112±0.03 0.319±0.06 0.034±0.02 0.428±0.07 0.009±0.00 0.108±0.08 0.020±0.01 0.018±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KT CIL_0007KT_0002 UCNEbase 12:107085268-108123079
CIL_00080U CIL_00080U_0002 VISTA 12:107477918-108078911
CIL_0005H1 CIL_0005H1_0002 CGP 12:107910403-108179314

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003334 IMP keratinocyte development
GO:0003382 IMP epithelial cell morphogenesis
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007409 IMP axonogenesis
GO:0008285 IDA negative regulation of cell proliferation
GO:0009791 IMP post-embryonic development
GO:0010468 IMP regulation of gene expression
GO:0010837 IMP regulation of keratinocyte proliferation
GO:0019216 IMP regulation of lipid metabolic process
GO:0021773 IMP striatal medium spiny neuron differentiation
GO:0021902 IGI commitment of neuronal cell to specific neuron type in forebrain
GO:0021953 IGI central nervous system neuron differentiation
GO:0031077 IMP post-embryonic camera-type eye development
GO:0033077 IMP T cell differentiation in thymus
GO:0033153 IMP T cell receptor V(D)J recombination
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0043066 IMP negative regulation of apoptotic process
GO:0043368 IMP positive T cell selection
GO:0043565 IDA sequence-specific DNA binding
GO:0043588 IMP skin development
GO:0045664 IMP regulation of neuron differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046632 IMP alpha-beta T cell differentiation
GO:0046872 IEA metal ion binding
GO:0048538 IMP thymus development
GO:0071678 IMP olfactory bulb axon guidance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000097543 BCL11B (2 of 2)-201 protein_coding Danio_rerio 0 370
ENSDART00000132521 bcl11aa-002 protein_coding Danio_rerio 0.00000000000001 88
ENSDART00000087426 bcl11aa-001 protein_coding Danio_rerio 0.00000000000001 88
ENST00000335712 BCL11A-001 protein_coding Homo_sapiens 0 270
ENST00000345514 BCL11B-002 protein_coding Homo_sapiens 0 2383
ENST00000356842 BCL11A-002 protein_coding Homo_sapiens 0 270
ENST00000357195 BCL11B-001 protein_coding Homo_sapiens 0 3217
ENST00000358510 BCL11A-006 protein_coding Homo_sapiens 0 270
ENST00000443726 BCL11B-003 protein_coding Homo_sapiens 0 2377
ENST00000477659 BCL11A-008 processed_transcript Homo_sapiens 0 270

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