C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: two pore segment channel 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000048677 Tpcn2 10090 - 7:145253923-145283927 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000058022 Tpcn2-201 145253923-145283927 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000058022
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000058022 6.826±2.25 3.715±1.24 6.645±1.93 0.726±0.23 4.965±1.75 4.500±0.86 1.572±0.35 1.696±0.44 1.317±0.49 8.355±1.33 0.358±0.18 6.943±2.42 2.124±0.64 2.645±1.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007TF CIL_0007TF_0002 VISTA 7:144693485-145297342
CIL_0007SN CIL_0007SN_0002 VISTA 7:144817158-145418950

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005245 IMP voltage-gated calcium channel activity
GO:0005515 IEA protein binding
GO:0005764 IDA lysosome
GO:0005765 IDA lysosomal membrane
GO:0005886 IBA plasma membrane
GO:0006874 IEA cellular calcium ion homeostasis
GO:0006939 IMP smooth muscle contraction
GO:0010008 IEA endosome membrane
GO:0016021 IEA integral component of membrane
GO:0019901 IEA protein kinase binding
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042802 IEA identical protein binding
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0070588 IEA calcium ion transmembrane transport
GO:0072345 IDA NAADP-sensitive calcium-release channel activity
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068381 tpcn2 two pore segment channel 2 protein_coding Danio_rerio
ENSG00000162341 TPCN2 two pore segment channel 2 protein_coding Homo_sapiens

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