C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: two pore segment channel 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000162341 TPCN2 9606 + 11:69048897-69090604 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000294309 TPCN2-001 69048897-69088524 protein_coding
  ENST00000442692 TPCN2-005 69055162-69090604 processed_transcript
  ENST00000534832 TPCN2-006 69049030-69054390 processed_transcript
  ENST00000535009 TPCN2-004 69048934-69079847 retained_intron
  ENST00000542467 TPCN2-003 69048961-69088203 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000294309ENST00000442692ENST00000542467
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000294309 1.125±0.00 3.517±0.00 0.273±0.00 1.806±0.00 0.330±0.19 0.625±0.00 3.420±0.00 0.576±0.00 1.191±0.00 0.485±0.00 3.268±0.86 2.802±0.31 1.781±0.76
ENST00000442692 0.537±0.00 0.737±0.00 0.237±0.00 1.334±0.00 N/A 0.596±0.00 1.760±0.00 N/A N/A 0.201±0.00 0.727±0.48 0.746±0.00 0.985±0.48
ENST00000542467 N/A N/A 0.837±0.00 N/A 0.533±0.00 N/A 0.365±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SN CIL_0007SN_0001 VISTA 11:68986730-69588911

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005764 IEA lysosome
GO:0005765 IDA lysosomal membrane
GO:0005886 IBA plasma membrane
GO:0006811 IEA ion transport
GO:0006816 IBA calcium ion transport
GO:0006874 IDA cellular calcium ion homeostasis
GO:0006939 ISS smooth muscle contraction
GO:0010008 IDA endosome membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019901 IPI protein kinase binding
GO:0034220 IBA ion transmembrane transport
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042802 IPI identical protein binding
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0055085 TAS:IEA transmembrane transport
GO:0070588 IEA calcium ion transmembrane transport
GO:0072345 IDA NAADP-sensitive calcium-release channel activity
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068381 tpcn2 two pore segment channel 2 protein_coding Danio_rerio
ENSMUSG00000048677 Tpcn2 two pore segment channel 2 protein_coding Mus_musculus

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