C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NK3 homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049691 Nkx3-2 10090 - 5:41761483-41764501 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000060820 Nkx3-2-001 41761483-41764501 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungOvaryPlacentaTestisENSMUST00000060820
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENSMUST00000060820 0.111±0.06 0.039±0.02 0.010±0.00 0.012±0.00 0.059±0.04 3.086±1.30 0.028±0.01 0.019±0.01 0.015±0.00 0.049±0.02 0.067±0.03 0.019±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00097J CIL_00097J_0002 VISTA 5:41437620-42039298
CIL_00026M CIL_00026M_0002 CGP 5:41624976-41764501
CIL_00026L CIL_00026L_0002 CGP 5:41761483-41844168

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001501 IMP skeletal system development
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007368 IMP determination of left/right symmetry
GO:0031016 IMP pancreas development
GO:0032331 IMP negative regulation of chondrocyte differentiation
GO:0042474 IMP middle ear morphogenesis
GO:0043066 IMP negative regulation of apoptotic process
GO:0048513 IMP organ development
GO:0048536 IMP spleen development
GO:0048645 IMP organ formation
GO:0048705 IMP skeletal system morphogenesis
GO:0048706 IMP embryonic skeletal system development
GO:0055123 IMP digestive system development
GO:0060576 IGI intestinal epithelial cell development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000037639 nkx3.2 NK3 homeobox 2 protein_coding Danio_rerio
ENSG00000109705 NKX3-2 NK3 homeobox 2 protein_coding Homo_sapiens

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