C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050069 Grem2 10090 - 1:174833785-174921819 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055294 Grem2-001 174833785-174921819 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055294
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055294 3.219±2.45 0.829±0.11 6.945±0.14 2.414±1.77 4.456±0.96 18.157±1.33 0.056±0.01 2.707±0.59 1.076±0.97 20.662±2.72 1.543±0.48 23.563±9.18 6.883±5.04 0.061±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KG CIL_0006KG_0002 CGP 1:174501825-174921819
CIL_0000L0 CIL_0000L0_0003 CGP 1:174833785-175491130

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005615 IMP extracellular space
GO:0008201 IDA heparin binding
GO:0010172 IMP embryonic body morphogenesis
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0030514 IMP negative regulation of BMP signaling pathway
GO:0036122 IMP BMP binding
GO:0038098 IMP sequestering of BMP from receptor via BMP binding
GO:0042803 IMP protein homodimerization activity
GO:0048263 IMP determination of dorsal identity
GO:0060300 IMP regulation of cytokine activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005001 grem2 gremlin 2, cysteine knot superfamily protein_coding Danio_rerio
ENSDARG00000056057 GREM2 (2 of 2) gremlin 2, DAN family BMP antagonist protein_coding Danio_rerio
ENSG00000180875 GREM2 gremlin 2, DAN family BMP antagonist protein_coding Homo_sapiens

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