C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000055294 Grem2-001 ENSMUSG00000050069 10090 - 1:174833785-174921819 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055294
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055294 3.219±2.45 0.829±0.11 6.945±0.14 2.414±1.77 4.456±0.96 18.157±1.33 0.056±0.01 2.707±0.59 1.076±0.97 20.662±2.72 1.543±0.48 23.563±9.18 6.883±5.04 0.061±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006KG CIL_0006KG_0002 CGP 1:174501825-174921819
CIL_0000L0 CIL_0000L0_0003 CGP 1:174833785-175491130

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005125 IEA cytokine activity
GO:0005615 IMP extracellular space
GO:0008201 IDA heparin binding
GO:0010172 IMP embryonic body morphogenesis
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0030514 IMP negative regulation of BMP signaling pathway
GO:0036122 IMP BMP binding
GO:0038098 IMP sequestering of BMP from receptor via BMP binding
GO:0042803 IMP protein homodimerization activity
GO:0048263 IMP determination of dorsal identity
GO:0060300 IMP regulation of cytokine activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000103870 GREM1 (2 of 3)-001 protein_coding Danio_rerio 9.99967e-42 176
ENST00000318160 GREM2-001 protein_coding Homo_sapiens 0 883

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