C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: secretogranin II
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000050711 Scg2 10090 - 1:79434669-79440120 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049972 Scg2-001 79434669-79440120 protein_coding
  ENSMUST00000185234 Scg2-002 79434669-79440042 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049972ENSMUST00000185234
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049972 N/A 12.362±2.93 0.131±0.01 8.220±1.99 N/A 0.459±0.19 N/A N/A 0.018±0.00 N/A N/A N/A N/A N/A
ENSMUST00000185234 0.038±0.02 16.614±5.87 0.069±0.00 39.737±44.66 0.036±0.00 1.497±0.31 0.022±0.01 0.083±0.03 0.028±0.02 0.038±0.02 0.017±0.01 0.123±0.05 0.019±0.01 0.157±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004AL CIL_0004AL_0003 CGP 1:78816758-79440120
CIL_0004AM CIL_0004AM_0004 CGP 1:79434669-79671972

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000165 ISS MAPK cascade
GO:0001525 IDA angiogenesis
GO:0001938 ISS positive regulation of endothelial cell proliferation
GO:0005125 ISS cytokine activity
GO:0005615 ISS extracellular space
GO:0006928 ISS cellular component movement
GO:0030141 IEA secretory granule
GO:0035556 ISS intracellular signal transduction
GO:0042056 ISS chemoattractant activity
GO:0048245 ISS eosinophil chemotaxis
GO:0050918 IEA positive chemotaxis
GO:0050930 ISS induction of positive chemotaxis
GO:2000352 ISS negative regulation of endothelial cell apoptotic process
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017470 scg2a secretogranin II (chromogranin C) a protein_coding Danio_rerio
ENSDARG00000038574 scg2b secretogranin II (chromogranin C), b protein_coding Danio_rerio
ENSG00000171951 SCG2 secretogranin II protein_coding Homo_sapiens

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