C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000051159 Cited1 10090 - X:102247381-102252181 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050551 Cited1-001 102247381-102252181 protein_coding
  ENSMUST00000101336 Cited1-002 102247404-102251852 protein_coding
  ENSMUST00000130589 Cited1-003 102247821-102250775 protein_coding
  ENSMUST00000134887 Cited1-005 102247714-102250946 protein_coding
  ENSMUST00000136277 Cited1-004 102247886-102251918 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000050551ENSMUST00000101336ENSMUST00000130589ENSMUST00000134887ENSMUST00000136277
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000050551 0.700±0.55 4.349±3.43 0.163±0.06 2.164±1.28 45.951±13.54 0.226±0.13 1.301±0.44 1.019±0.48 21.401±24.35 0.110±0.07 0.177±0.09 7.004±3.51 320.058±256.62 27.451±12.14
ENSMUST00000101336 0.389±0.02 0.903±0.43 0.069±0.00 1.072±0.53 N/A 0.073±0.03 N/A 0.345±0.21 N/A 0.081±0.01 N/A 1.749±0.59 N/A N/A
ENSMUST00000130589 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.164±0.00 N/A N/A N/A
ENSMUST00000134887 N/A 2.423±0.37 N/A N/A 11.213±0.00 N/A N/A 0.523±0.00 N/A N/A 0.207±0.00 1.446±0.00 N/A N/A
ENSMUST00000136277 N/A N/A N/A 1.117±0.00 N/A 0.554±0.00 N/A N/A N/A 0.100±0.00 N/A 8.802±0.00 310.482±205.85 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YL CIL_0000YL_0003 CGP X:102184941-102252181
CIL_0006RM CIL_0006RM_0002 CGP X:102247381-102505359

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000578 IEA embryonic axis specification
GO:0001570 IMP vasculogenesis
GO:0001658 IEA branching involved in ureteric bud morphogenesis
GO:0001890 IMP placenta development
GO:0003340 IEA negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0003682 IDA chromatin binding
GO:0003700 NAS sequence-specific DNA binding transcription factor activity
GO:0003713 ISS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006913 ISS nucleocytoplasmic transport
GO:0006915 IEA apoptotic process
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007420 IEP brain development
GO:0008022 IEA protein C-terminus binding
GO:0010628 IDA positive regulation of gene expression
GO:0030318 IMP melanocyte differentiation
GO:0032496 IDA response to lipopolysaccharide
GO:0032868 IDA response to insulin
GO:0034097 IDA response to cytokine
GO:0034341 IDA response to interferon-gamma
GO:0042438 IDA melanin biosynthetic process
GO:0042803 ISS protein homodimerization activity
GO:0043473 IDA pigmentation
GO:0043524 ISS negative regulation of neuron apoptotic process
GO:0043627 IEA response to estrogen
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045668 IMP negative regulation of osteoblast differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0050693 IEA LBD domain binding
GO:0051591 IDA response to cAMP
GO:0060395 IEA SMAD protein signal transduction
GO:0060711 IMP labyrinthine layer development
GO:0060712 IMP spongiotrophoblast layer development
GO:0070410 IEA co-SMAD binding
GO:0070555 IDA response to interleukin-1
GO:0070669 IDA response to interleukin-2
GO:0070670 IDA response to interleukin-4
GO:0070741 IDA response to interleukin-6
GO:0071104 IDA response to interleukin-9
GO:0071105 IDA response to interleukin-11
GO:0071107 IDA response to parathyroid hormone
GO:0071559 ISS response to transforming growth factor beta

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077769 cited1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 protein_coding Danio_rerio
ENSG00000125931 CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 protein_coding Homo_sapiens

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