C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: roundabout homolog 2 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052516 Robo2 10090 - 16:73892306-74411825 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000116586 Robo2-002 73920206-74411785 protein_coding
  ENSMUST00000117200 Robo2-004 73894355-74411292 protein_coding
  ENSMUST00000117785 Robo2-001 73892306-74410989 protein_coding
  ENSMUST00000137420 Robo2-009 73897030-73906999 processed_transcript
  ENSMUST00000138852 Robo2-008 73920461-73933076 retained_intron
  ENSMUST00000140062 Robo2-005 74044072-74411437 retained_intron
  ENSMUST00000147408 Robo2-007 73982101-74027889 processed_transcript
  ENSMUST00000149114 Robo2-003 73894664-73899885 retained_intron
  ENSMUST00000156010 Robo2-006 74349795-74411825 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000116586ENSMUST00000117200ENSMUST00000117785ENSMUST00000137420ENSMUST00000138852ENSMUST00000140062ENSMUST00000156010
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000116586 0.979±0.88 0.153±0.10 0.320±0.06 6.001±1.83 0.310±0.22 0.788±0.04 0.133±0.01 1.158±0.15 0.175±0.09 1.995±0.07 0.017±0.00 1.186±0.27 0.165±0.05 0.091±0.09
ENSMUST00000117200 1.809±1.22 0.150±0.08 0.887±0.04 14.039±3.87 0.319±0.13 1.290±0.41 0.083±0.00 2.150±0.51 0.470±0.30 2.259±0.52 0.037±0.03 1.850±1.06 0.239±0.07 0.025±0.01
ENSMUST00000117785 0.840±0.00 0.145±0.00 N/A 6.998±6.02 0.128±0.03 0.495±0.09 0.015±0.00 0.636±0.00 0.189±0.06 0.857±0.05 0.014±0.00 0.523±0.10 0.046±0.00 0.010±0.00
ENSMUST00000137420 N/A 0.523±0.22 N/A N/A 1.671±0.00 7.438±0.00 N/A N/A 0.682±0.00 N/A 0.335±0.00 6.024±0.90 N/A N/A
ENSMUST00000138852 N/A N/A N/A N/A 1.464±0.00 11.115±0.28 0.299±0.00 N/A 0.396±0.00 N/A 0.223±0.09 N/A N/A 0.219±0.10
ENSMUST00000140062 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.012±0.00
ENSMUST00000156010 N/A 0.265±0.17 N/A N/A N/A N/A N/A N/A N/A N/A 0.009±0.00 1.945±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00031Z CIL_00031Z_0002 CGP 16:72663149-74411825

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001656 IMP metanephros development
GO:0001657 IEA ureteric bud development
GO:0007156 IEA homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007411 IMP axon guidance
GO:0007420 IEA brain development
GO:0009986 IEA cell surface
GO:0030673 IDA axolemma
GO:0032870 IEA cellular response to hormone stimulus
GO:0042802 IEA identical protein binding
GO:0050772 IEA positive regulation of axonogenesis
GO:0050925 IEA negative regulation of negative chemotaxis
GO:0061364 IEA apoptotic process involved in luteolysis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014891 robo2 roundabout homolog 2 protein_coding Danio_rerio
ENSDARG00000078366 robo2 roundabout homolog 2 protein_coding Danio_rerio
ENSG00000185008 ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) protein_coding Homo_sapiens

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