C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: G protein-coupled receptor kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000001112 Grk4-001 ENSMUSG00000052783 10090 + 5:34660379-34755303 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001112
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001112 0.360±0.06 1.023±0.32 1.307±0.30 0.375±0.00 0.543±0.24 0.730±0.48 0.117±0.04 0.192±0.03 0.196±0.15 0.495±0.17 0.245±0.09 0.849±0.32 0.158±0.09 20.064±6.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00056M CIL_00056M_0002 CGP 5:34638532-34755305
CIL_000748 CIL_000748_0002 CGP 5:34660379-34912534

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002029 IEA desensitization of G-protein coupled receptor protein signaling pathway
GO:0002031 IEA G-protein coupled receptor internalization
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0005524 IEA ATP binding
GO:0005829 IEA cytosol
GO:0007165 IEA signal transduction
GO:0030425 IEA dendrite
GO:0031623 IEA receptor internalization
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043025 IEA neuronal cell body
GO:0050254 IEA rhodopsin kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000345167 GRK4-005 protein_coding Homo_sapiens 0 1328
ENST00000398051 GRK4-002 protein_coding Homo_sapiens 0 1269
ENST00000398052 GRK4-001 protein_coding Homo_sapiens 0 1389
ENST00000504933 GRK4-012 protein_coding Homo_sapiens 0 1330

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