C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor, erythroid derived 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000058794 Nfe2 10090 - 15:103248212-103258403 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000075192 Nfe2-001 103248212-103255439 protein_coding
  ENSMUST00000131364 Nfe2-010 103249007-103254062 protein_coding
  ENSMUST00000132438 Nfe2-006 103249349-103258403 protein_coding
  ENSMUST00000132836 Nfe2-009 103249069-103251687 protein_coding
  ENSMUST00000133600 Nfe2-003 103248217-103251465 protein_coding
  ENSMUST00000134193 Nfe2-007 103248955-103253152 protein_coding
  ENSMUST00000134554 Nfe2-004 103248275-103251515 protein_coding
  ENSMUST00000149111 Nfe2-002 103248220-103251676 protein_coding
  ENSMUST00000154510 Nfe2-008 103249239-103252810 protein_coding
  ENSMUST00000156927 Nfe2-005 103248217-103251516 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000075192ENSMUST00000131364ENSMUST00000132836ENSMUST00000133600ENSMUST00000134193ENSMUST00000134554ENSMUST00000149111ENSMUST00000154510ENSMUST00000156927
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000075192 1.147±0.68 0.343±0.13 0.055±0.00 0.102±0.06 0.803±0.18 0.323±0.14 0.379±0.07 0.203±0.03 50.877±61.15 4.292±0.81 N/A 0.659±0.21 2.823±2.25 0.494±0.11
ENSMUST00000131364 N/A N/A N/A 0.041±0.00 0.585±0.20 N/A N/A N/A N/A N/A N/A 0.416±0.10 N/A N/A
ENSMUST00000132836 N/A N/A N/A 0.075±0.00 0.795±0.00 0.339±0.04 N/A 0.126±0.00 N/A N/A N/A 0.143±0.00 N/A N/A
ENSMUST00000133600 N/A N/A N/A 0.014±0.00 N/A N/A N/A N/A N/A N/A N/A 0.063±0.00 1.323±0.00 N/A
ENSMUST00000134193 0.128±0.00 N/A N/A N/A 0.321±0.01 0.322±0.00 N/A N/A 0.846±0.33 N/A N/A 0.259±0.00 1.430±0.00 N/A
ENSMUST00000134554 N/A 0.073±0.02 0.054±0.00 N/A 0.211±0.07 N/A N/A 0.071±0.01 N/A N/A 0.015±0.00 0.198±0.14 N/A N/A
ENSMUST00000149111 N/A N/A N/A N/A N/A N/A 0.144±0.04 N/A N/A N/A N/A 0.126±0.02 0.769±0.32 N/A
ENSMUST00000154510 N/A N/A N/A N/A N/A N/A 0.302±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000156927 N/A 0.234±0.00 N/A N/A N/A 0.111±0.00 N/A N/A 0.345±0.06 N/A N/A 0.389±0.14 1.797±0.00 0.570±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SU CIL_0007SU_0002 VISTA 15:102699781-103302958
CIL_00084M CIL_00084M_0002 VISTA 15:102713812-103314964
CIL_0002TL CIL_0002TL_0003 CGP 15:103240432-103258403
CIL_0002TK CIL_0002TK_0003 CGP 15:103248212-103299862

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007267 IMP cell-cell signaling
GO:0015629 IEA actin cytoskeleton
GO:0030502 IMP negative regulation of bone mineralization
GO:0034242 IGI negative regulation of syncytium formation by plasma membrane fusion
GO:0043565 IEA sequence-specific DNA binding
GO:0047485 IEA protein N-terminus binding
GO:0050699 IEA WW domain binding
GO:0060716 IMP labyrinthine layer blood vessel development
GO:2000758 IMP positive regulation of peptidyl-lysine acetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020606 nfe2 nuclear factor, erythroid-derived 2 protein_coding Danio_rerio
ENSG00000123405 NFE2 nuclear factor, erythroid 2 protein_coding Homo_sapiens

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