C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear factor, erythroid 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000123405 NFE2 9606 - 12:54292111-54301121 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000312156 NFE2-003 54292111-54295760 protein_coding
  ENST00000435572 NFE2-001 54292111-54301121 protein_coding
  ENST00000540264 NFE2-004 54292173-54295758 protein_coding
  ENST00000553070 NFE2-002 54292374-54301015 protein_coding
  ENST00000553198 NFE2-005 54292465-54297884 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000312156ENST00000435572ENST00000553070ENST00000553198
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000312156 N/A N/A N/A N/A N/A 0.212±0.00 N/A N/A N/A 1.563±0.00 N/A N/A 0.952±0.49 N/A
ENST00000435572 0.787±0.00 N/A N/A 0.144±0.00 0.371±0.00 N/A 0.195±0.13 N/A 0.448±0.12 5.360±4.40 N/A 0.164±0.00 2.235±0.60 0.836±0.19
ENST00000553070 0.342±0.00 N/A N/A 0.187±0.00 N/A 0.351±0.00 N/A 0.165±0.00 0.073±0.00 N/A N/A 0.241±0.09 N/A N/A
ENST00000553198 0.351±0.00 0.053±0.00 0.352±0.00 N/A 0.098±0.00 0.127±0.00 N/A N/A N/A 0.314±0.00 0.385±0.00 0.108±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007SU CIL_0007SU_0001 VISTA 12:53718454-54321661
CIL_00084M CIL_00084M_0001 VISTA 12:53732854-54334005
CIL_0002TL CIL_0002TL_0002 CGP 12:54280193-54301121
CIL_0002TK CIL_0002TK_0002 CGP 12:54292111-54351849

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003713 TAS transcription coactivator activity
GO:0005515 IEA protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006337 TAS nucleosome disassembly
GO:0006351 TAS transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007267 IEA cell-cell signaling
GO:0007275 TAS multicellular organismal development
GO:0007596 TAS blood coagulation
GO:0007599 TAS hemostasis
GO:0008015 TAS blood circulation
GO:0015629 IDA actin cytoskeleton
GO:0030502 IEA negative regulation of bone mineralization
GO:0034242 IEA negative regulation of syncytium formation by plasma membrane fusion
GO:0043565 IEA:TAS sequence-specific DNA binding
GO:0045893 TAS positive regulation of transcription, DNA-templated
GO:0047485 IPI protein N-terminus binding
GO:0050699 IDA WW domain binding
GO:0060716 IEA labyrinthine layer blood vessel development
GO:2000758 IEA positive regulation of peptidyl-lysine acetylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020606 nfe2 nuclear factor, erythroid-derived 2 protein_coding Danio_rerio
ENSMUSG00000058794 Nfe2 nuclear factor, erythroid derived 2 protein_coding Mus_musculus

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