C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, light polypeptide 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000061086 Myl4 10090 + 11:104550663-104595753 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018800 Myl4-001 104550663-104587215 protein_coding
  ENSMUST00000106956 Myl4-004 104577281-104587215 protein_coding
  ENSMUST00000106957 Myl4-003 104576985-104587215 protein_coding
  ENSMUST00000123074 Myl4-006 104580325-104587209 retained_intron
  ENSMUST00000130588 Myl4-005 104577017-104585014 nonsense_mediated_decay
  ENSMUST00000136244 Myl4-008 104584964-104595753 protein_coding
  ENSMUST00000153761 Myl4-007 104575446-104585748 protein_coding
  ENSMUST00000155271 Myl4-002 104582039-104586347 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018800ENSMUST00000106956ENSMUST00000106957ENSMUST00000123074ENSMUST00000130588ENSMUST00000153761ENSMUST00000155271
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018800 N/A N/A N/A N/A 0.274±0.00 N/A N/A 0.263±0.00 0.122±0.00 N/A N/A 2.116±0.98 N/A 17.395±5.85
ENSMUST00000106956 3.307±0.28 N/A 34.372±0.26 0.773±0.09 1.047±0.52 1.687±0.35 573.537±82.89 0.379±0.00 2.098±2.69 79.419±5.52 6.534±1.27 1.162±0.13 34.853±45.14 N/A
ENSMUST00000106957 3.342±0.95 N/A N/A N/A 0.830±0.51 0.217±0.00 N/A 0.287±0.00 0.652±0.35 N/A 2.212±0.71 N/A 26.370±21.00 N/A
ENSMUST00000123074 5.257±3.36 0.444±0.33 8.292±0.00 5.357±6.84 1.085±0.43 0.659±0.15 N/A 0.692±0.38 0.713±0.92 22.156±0.00 N/A 4.633±1.46 13.357±6.21 7.907±1.34
ENSMUST00000130588 N/A 0.285±0.04 N/A N/A 0.285±0.00 N/A N/A N/A N/A N/A N/A 1.094±0.00 N/A N/A
ENSMUST00000153761 N/A 0.378±0.10 N/A 19.801±0.00 0.604±0.19 0.732±0.02 N/A 0.435±0.16 0.236±0.12 N/A N/A 2.480±1.62 29.455±8.88 25.600±0.00
ENSMUST00000155271 0.519±0.04 0.107±0.05 1.558±0.00 0.098±0.02 0.266±0.08 0.107±0.03 11.167±0.00 0.067±0.03 0.056±0.03 N/A N/A 0.390±0.12 1.478±0.92 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HD CIL_0008HD_0002 VISTA 11:104342398-104943585
CIL_0002QR CIL_0002QR_0002 CGP 11:104502745-104595753
CIL_0004WN CIL_0004WN_0002 CGP 11:104550663-104670476

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002026 IEA regulation of the force of heart contraction
GO:0003785 IEA actin monomer binding
GO:0005509 IEA calcium ion binding
GO:0031672 IEA A band
GO:0032781 IEA positive regulation of ATPase activity
GO:0051015 IEA actin filament binding
GO:0060048 IEA cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011519 myl4 myosin, light chain 4, alkali; atrial, embryonic protein_coding Danio_rerio
ENSDARG00000032976 cmlc1 cardiac myosin light chain-1 protein_coding Danio_rerio
ENSG00000198336 MYL4 myosin, light chain 4, alkali; atrial, embryonic protein_coding Homo_sapiens

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