C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myosin, light chain 4, alkali; atrial, embryonic
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198336 MYL4 9606 + 17:47200446-47223679 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354968 MYL4-201 47209062-47223678 protein_coding
  ENST00000393450 MYL4-001 47209348-47223679 protein_coding
  ENST00000536623 MYL4-004 47209066-47223038 protein_coding
  ENST00000570671 MYL4-006 47220030-47223477 protein_coding
  ENST00000570772 MYL4-008 47209063-47221851 nonsense_mediated_decay
  ENST00000571981 MYL4-007 47200446-47223672 nonsense_mediated_decay
  ENST00000572303 MYL4-005 47209400-47221796 protein_coding
  ENST00000572316 MYL4-002 47209035-47223658 protein_coding
  ENST00000573747 MYL4-009 47209342-47223057 nonsense_mediated_decay
  ENST00000576874 MYL4-003 47209066-47222409 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354968ENST00000393450ENST00000536623ENST00000570671ENST00000570772ENST00000572316ENST00000573747ENST00000576874
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354968 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.049±0.00
ENST00000393450 N/A 1.268±0.00 N/A 0.714±0.00 0.683±0.00 58.960±50.28 N/A N/A N/A N/A N/A 2.799±2.49 1.148±0.00
ENST00000536623 0.267±0.00 N/A N/A 0.672±0.00 N/A N/A N/A 0.285±0.00 N/A N/A 0.180±0.00 2.470±0.47 N/A
ENST00000570671 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.188±0.00 N/A N/A
ENST00000570772 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.949±0.00
ENST00000572316 0.863±0.00 0.686±0.00 N/A N/A 0.670±0.00 N/A 0.316±0.00 N/A 5.815±0.00 1.408±0.00 N/A 4.121±0.00 2.742±0.00
ENST00000573747 N/A N/A 0.121±0.00 0.754±0.00 0.266±0.00 75.366±0.00 N/A N/A 5.302±0.00 0.322±0.00 N/A 0.582±0.00 N/A
ENST00000576874 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.449±0.00 2.354±0.00 2.106±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HD CIL_0008HD_0001 VISTA 17:46991162-47592148
CIL_0002QR CIL_0002QR_0001 CGP 17:47117703-47223679
CIL_0004WN CIL_0004WN_0001 CGP 17:47200446-47311816

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002026 IMP regulation of the force of heart contraction
GO:0003785 IDA actin monomer binding
GO:0005509 IEA calcium ion binding
GO:0005829 TAS cytosol
GO:0016459 IEA myosin complex
GO:0030049 TAS muscle filament sliding
GO:0031672 IMP A band
GO:0032038 NAS myosin II heavy chain binding
GO:0032781 IMP positive regulation of ATPase activity
GO:0051015 IMP actin filament binding
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011519 myl4 myosin, light chain 4, alkali; atrial, embryonic protein_coding Danio_rerio
ENSDARG00000032976 cmlc1 cardiac myosin light chain-1 protein_coding Danio_rerio
ENSMUSG00000061086 Myl4 myosin, light polypeptide 4 protein_coding Mus_musculus

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